DPHARM 2025 Highlights: How AI and Patient-Centric Solutions Are Shaping Clinical Research
The 15th annual DPHARM: Disruptive Innovations to Modernize Clinical Research (September 16–17, 2025, Philadelphia, PA) brought together senior clinical operations executives, patient advocates, and technology leaders to explore the future of clinical trials. AI, patient-centric trial design, decentralized trials, and purpose-driven innovation emerged as key themes shaping the next generation of research.
TrialX attended as an exhibiting sponsor, with our team on the ground including Co-founder & CEO, Dr. Sharib Khan, Co-founder & CTO, Dr. Chintan Patel, VP of Business Development, Beth Dickson, and Senior Director, Wes Martz. We engaged with peers and stakeholders at our booth, discussing how AI-powered solutions can enhance clinical research on Earth and in space.
Key Trends and Takeaways from DPHARM 2025
1. AI Moves from Hype to Real-World Impact
- Autonomous and agentic AI platforms streamline workflows, dynamically adapt protocols, and provide actionable insights for faster, smarter trials.
- AI-assisted regulatory writing accelerates document creation and enhances compliance.
- Predictive patient enrollment and DEI-focused tools optimize recruitment and ensure trial diversity.
2. Decentralized & Hybrid Trials Gain Momentum
- Trials increasingly meet patients where they live, including at home via connected devices.
- Real-world data (RWD) from wearables enables adaptive and inclusive trial designs.
- Regulatory frameworks, including guidance from the FDA, support decentralized trial elements and RWD integration.
3. Patient-Centric Design Takes Center Stage
- Platforms like TrialHub, winner of DPHARM Idol Disrupt 2025, adapt protocols to fit real patient journeys, optimizing recruitment and site selection.
- The emphasis is on creating trials that accommodate patients’ lives rather than expecting patients to fit into rigid protocols.
4. Operational Efficiency & Workforce Optimization
- The industry continues to face shortages of clinical investigators and research coordinators.
- Cloud-based and AI-powered solutions reduce administrative burden, streamline operations, and expand global trial capabilities.
5. Purpose-Driven Innovation
- Keynote speakers including Kenneth C. Frazier (former Merck CEO) and Scott Gottlieb, MD (former FDA Commissioner) emphasized leveraging disruption to drive meaningful innovation.
- Patient advocate Victoria Gray shared insights from her CRISPR gene therapy trial, highlighting the impact of patient-centered research.
TrialX at DPHARM 2025: Engaging and Connecting
TrialX participated as an exhibiting sponsor, connecting with industry peers to discuss our AI-driven solutions for patient recruitment, remote data collection, and space health research. Our team actively networked with attendees and shared how our technology supports clinical research and space medicine initiatives.
DPHARM 2025 proved to be a very productive event, with valuable conversations across the industry. Our team had the opportunity to connect with representatives from Merck, Novartis, IMO Health, Regeneron, AbbVie, Sanofi, Bayer, and more. One highlight was a session led by Sean Lynch from Novartis on trial matching, which resonated strongly with our mission to simplify participant recruitment. Additionally, our leadership attended several other sessions, bringing back insights on how AI is shaping nearly every aspect of clinical research. Across the event, AI was not only a central theme but also a key driver in the solutions presented by nearly every vendor.
Our Solutions
Patient Recruitment Management Platform
We help sponsors, academic centers, and advocacy groups connect patients with the right studies faster. Our AI-powered trial finders, participant-friendly content, multilingual study websites, and AI navigators simplify trial discovery and engagement. Trusted by leading organizations like the University of Pennsylvania, NYU Langone, Indiana University CTSI, the Michael J. Fox Foundation, and top pharma companies, our platform has powered finders for advocacy groups including Reflections Collective, Let’s Win PC, ALS Network, and Beyond Celiac.
Remote Data Collection Platform
Our platform makes clinical trial participation seamless by enabling remote e-consent, pre-screening, and data capture across ePRO, eCOA, and ClinRO. Integrated with wearables and medical devices, it ensures richer datasets—even offline in bandwidth-limited environments such as space missions. TrialX technology has already supported missions like Inspiration4, Polaris, and four Axiom missions, advancing remote research for both space health and Earth-based healthcare.
Space Health Research
As pioneers in space health informatics, we support astronauts in tracking and transmitting health data to generate insights that benefit both space travelers and patients on Earth. In partnership with the Translational Research Institute for Space Health (TRISH), MIT, and Caltech, we continue to advance this frontier with tools like the EXPAND database and HERMES platform, recently highlighted at NASA’s Human Research Program Investigators’ Workshop.
Broader Impacts of AI in Clinical Research
DPHARM 2025 emphasized AI’s transformative role across the clinical research ecosystem:
- Agentic AI for real-time insights and streamlined workflows.
- Generative AI enabling hyper-personalized medicine and predictive outcomes.
- Regulatory frameworks evolving to ensure trustworthy and explainable AI.
- AI applications extend beyond R&D into commercial strategy, from market insights to automated decision-making.
Driving Patient-Centric and AI-Powered Trials
DPHARM 2025 reinforced a central theme: clinical research must be both patient-centric and technologically empowered, leveraging AI to streamline trials, enhance engagement, and generate actionable insights. At TrialX, we’re committed to driving this vision forward by supporting more inclusive, efficient, and innovative clinical trials—on Earth and in space. We look forward to continuing these conversations—and seeing you all next year!
——————————————————————————————————–
TrialX at DPharm 2025 – Leveraging AI to Advance Patient Recruitment, Remote Data Collection & Space Health Research
TrialX is attending DPharm 2025 in Philadelphia, September 16–17, as an exhibiting sponsor! Join us to explore how our AI innovations in patient recruitment, remote data collection, and space health research are advancing clinical trials on Earth and in space. Our team including our co-founder & CEO, Sharib Khan would love to meet if you are visiting!
👉 Schedule a meeting with TrialX at DPharm 2025
Powering Clinical Research on Earth and in Space
Since launching the first clinical trials app on Google Health in 2008, TrialX has been at the forefront of simplifying and advancing clinical research. Our mission is to help sponsors, academic medical centers, and advocacy groups overcome the most pressing challenges in clinical trials— patient engagement, clinical trial recruitment and digital data collection—while also supporting groundbreaking health research for commercial space missions.
Our Solutions
Patient Recruitment Management Platform
Our recruitment platform connects patients with the right studies faster and more effectively. With AI-powered trial finders, simplified participant-friendly content, a study website builder supporting multiple languages, AI patient navigators, and smarter trial matching using health record data, we empower sponsors, academic centers, and advocacy groups to engage participants at scale. Organizations such as University of Pennsylvania, NYU Langone, Indiana University CTSI, 2 of top 5 pharma companies, and the Michael J. Fox Foundation trusts our platform, which recently powered the clinical trial finders for several advocacy organizations including Reflections Collective, Let’s Win PC, ALS Network, Beyond Celiac and more.
Remote Data Collection Platform
Our remote data capture platform is designed to make clinical trial participation seamless and inclusive. It simplifies recruitment with automated pre-screening, eligibility checks, and remote e-consent, while supporting comprehensive data capture across ePRO, eCOA, and ClinRO. The platform integrates seamlessly with wearables and medical devices—from Garmin trackers to handheld ultrasounds—enabling richer, more continuous datasets. Even in bandwidth-limited environments, including space missions, participants can collect data offline and sync it later without disruption. Real-time dashboards provide actionable insights, allowing study teams to track progress, participant well-being, and data quality at every step.
Space Health Research
As pioneers in space health informatics, TrialX is proud to support groundbreaking studies that advance human health in extreme environments. Our technology enables astronauts to track and transmit health data during commercial space missions, generating insights that benefit both space travelers and patients on Earth. From monitoring physiological changes in microgravity to building infrastructure for space-based medical research, TrialX is helping push the frontiers of medicine. At NASA’s Human Research Program Investigators’ Workshop (HRP IWS) 2025, our teams showcased two cutting-edge technologies developed in partnership with TRISH to advance space health research – the EXPAND database and the HERMES platform.
TrialX Space Health System has already supported health data collection for commercial missions such as Inspiration4, Polaris Dawn, Fram2, and the four Axiom missions. In collaboration with the Translational Research Institute for Space Health we continue to push the boundaries of how remote data informs both space medicine and healthcare on Earth.
Let’s Meet at DPharm
We’d love to connect with you at the conference. Schedule a time to meet with our team to learn how we can support your clinical research with innovative, scalable solutions.
👉 Schedule a meeting with us at DPharm 2025
Follow us on LinkedIn for updates and highlights during the conference with the hashtag #dpharm2025. We look forward to seeing you in Philadelphia!
