Polycystic ovary syndrome (PCOS) is a health condition that affects 1 in 10 women of childbearing age. Women with PCOS have a hormonal imbalance and metabolism problems that may lead to obesity, cardiovascular disease, type 2 diabetes, infertility, endometrial cancer and more. In the absence of a complete cure, efficient management of the condition gains importance and information is the key. We are talking to a panel of PCOS experts from the University of Pennsylvania to understand the condition, available treatments, and best ways to manage symptoms. The discussion will also touch upon the details of the PCOS-COMET study being conducted by Penn PCOS Center to compare the effects of medications on metabolic risk factors such as weight, blood pressure, glucose, and cholesterol levels in overweight/obese women with Dr. Anuja Dokras, Director PCOS Center, and principal investigator of study. Dr. Anastassia Amaro and Dr. Kelly Costello Allison from the Center for Weight and Eating Disorder of University of Pennsylvania will help us take a deep dive to understand the nuances of weight, nutrition, psychology and related effects on PCOS and its management.