What is Secnidazole (Flagentyl and Sindose)?
Secnidazole belongs to category of antiprotozoal agents drugs. Secnidazole is a type of potentiate anticoagulant effect of warfarin. concurrent disulfîram may cause antabuse-like effects cimetidine prolongs half-life.
It belongs to 5 nitroimidazole, effective in intestinal ameobiasis, giardiasis, trichomoniasis or bacterial vaginosis with a single once only dose.
Secnidazole is a nitroimidazole anti-infective. Effectiveness in the treatment of dientamoebiasis has been reported. It has also been tested against Atopobium vaginae. This drug is commonly sold as Brand Name Flagentyl.
Indication/Contraindication for use of Secnidazole (Flagentyl and Sindose)
- Intestinal amoebiasis, Hepatic amoe biasis, giardiasis, trichomonal vagnitis, bacterial vaginosis.
- Pregnancy, lactation, hypersensitivity.
Side Effects of Secnidazole (Flagentyl and Sindose)
Nausea, epigastric pain, glossitis, fatigue, head ache, loss of appetite, diarrhea stomatitis, urticaria rash & leucopenia
Dosage and Prescribing Information for Secnidazole (Flagentyl and Sindose)
Intestinal amoebiasis & giardiasis: 1 day treatment (Adults 2 gms. Children 30 mg/Kg body wt) as single once only dosage.
Drug Interactions of Secnidazole (Flagentyl and Sindose)
Potentiate anticoagulant effect of warfarin. Concurrent disulfîram may cause ant-abuse like effects Cimetidine prolongs halflife.
Precautions while prescribing Secnidazole (Flagentyl and Sindose)
- diseases, liver im pairment, alcoholic beverage.