Secnidazole (Flagentyl and Sindose) Side Effects, Dosage, Interaction Information

Feb 13, 2011 No Comments by

What is Secnidazole (Flagentyl and Sindose)?

Secnidazole belongs to category of antiprotozoal agents drugs. Secnidazole is a type of potentiate anticoagulant effect of warfarin. concurrent disulfîram may cause antabuse-like effects cimetidine prolongs half-life.

It belongs to 5 nitroimidazole, effective in intestinal ameobiasis, giardiasis, trichomoniasis or bacterial vaginosis with a single once only dose.

Secnidazole is a nitroimidazole anti-infective. Effectiveness in the treatment of dientamoebiasis has been reported. It has also been tested against Atopobium vaginae. This drug is commonly sold as Brand Name Flagentyl.

Indication/Contraindication for use of Secnidazole (Flagentyl and Sindose)

  • Intestinal amoebiasis, Hepatic amoe biasis, giardiasis, trichomonal vagnitis, bacterial vaginosis.
  • Pregnancy, lactation, hypersensitivity.

Side Effects of Secnidazole (Flagentyl and Sindose)

Nausea, epigastric pain, glossitis, fatigue, head ache, loss of appetite, diarrhea stomatitis, urticaria rash & leucopenia

Dosage and Prescribing Information for Secnidazole (Flagentyl and Sindose)

Intestinal amoebiasis & giardiasis: 1 day treatment (Adults 2 gms. Children 30 mg/Kg body wt) as single once only dosage.

Drug Interactions of Secnidazole (Flagentyl and Sindose)

Potentiate anticoagulant effect of warfarin. Concurrent disulfîram may cause ant-abuse like effects Cimetidine prolongs halflife.

Precautions while prescribing Secnidazole (Flagentyl and Sindose)

  • N
  • C
  • diseases, liver im pairment, alcoholic beverage.
  • S
Antibiotics

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