What is Niclosamide (Niclocide)?
Niclosamide is a type of alcohol may enhance absorption of the drug. Niclosamide belongs to category of anthelmintics drugs.
Highly effective drug against cestodes infesting man Tania Saginate, T. Solium, Diphyllobothrium latum and Hymenolepiasis nana. as well as thread worm. A saline purgative is given 2 hours after the dose to wash off the worm. Niclosamide is used specifically to treat tapeworms and is not effective against worms such as pin-worms or roundworms. It is a chewable tablet taken orally, dosage depending on type of worm and patient’s age and/or weight. Niclosamide molecules are lethal to tapeworms upon contact. This drug is commonly sold as Brand Name Niclocide.
Indication/Contraindication for use of Niclosamide (Niclocide)
- Taenia sodium.
- Taenia saginata.
- Di phyllobothrium la-tum, Hymenolepis nana.
Side Effects of Niclosamide (Niclocide)
- upset, pruritus.
Dosage and Prescribing Information for Niclosamide (Niclocide)
Adults and children over 6 yrs: 1gm followed by another dose of 1 gm one hour later. Single dose of 2 gm may also be given. Brisk purgative after 2 hours of last dose recommended. Children: (26yrs) 1 gm total dose in 2 divided doses.
Drug Interactions of Niclosamide (Niclocide)
Alcohol may enhance absorption of the drug.
Precautions while prescribing Niclosamide (Niclocide)
- Lactation: Use with caution.
- Digestion of the dead seg ments of injured T.
- Pregnancy: Use with caution.
- Elderly: Safe.
- Solium can be hazardous, as the ova released from them may develop into larvae in the intestine, penetrate its wall and cause visceral cysticercosis, thus a thorough purge is essential: The scolex should be searched in the stools to be sure that the worm will not grow again.
- Paediatrics: Use with caution.