What is Mebendazole (Bantenol and Besantin)?
Mebendazole is a type of carbamates. Mebendazole belongs to category of anthelmintics drugs.
It has produced nearly 100% cure rate/ reduction/in egg count in round worm, hook worm. (both species), Enterobius and Trichuris infestations. Upto 75% patients are also card of strongyloides and tape worms: H. nana is relatively insensitive. It expells Trichinella spiralis from intes tinas, but efficacy in killing lariae that have migrated to muscles is uncertain. Prolonged treatment has been shown to cause regression of hydatid cysts in the liver: surgery may thus be avoided. It acts probably by blocking glucose uptake in parasite and depletion of its glycogen stores. About 90% of an oral dose is passed in the faeces. Mebendazole or MBZ, marketed as Ovex, Vermox, Antiox, Pripsen, is a benzimidazole drug that is used to treat infestations by worms including pinworms, roundworms, tapeworms, hookworms, and whipworms.
This drug is commonly sold as Brand Name Bantenol.
Indication/Contraindication for use of Mebendazole (Bantenol and Besantin)
- Round worm, hookworm, whip worm, mixed infestations, threadworm and tapeworm.
Side Effects of Mebendazole (Bantenol and Besantin)
- Diarrhea, nausea, abdominal pain, allergic reactions, loss of hair and granulocytopenia with high doses.
Dosage and Prescribing Information for Mebendazole (Bantenol and Besantin)
100 mg twice daily for 5 day. Thread worm: Single dose of 100 mg. Tapeworm: 200 mg twice daily for 3 days.
Drug Interactions of Mebendazole (Bantenol and Besantin)
Absorption increased in the presence of fatty food.
Precautions while prescribing Mebendazole (Bantenol and Besantin)
Lactation Expulsion of As caries from mouth or nose may occur.