Ethamsylate (Etamsylate and Dicynene) Side Effects, Indications, Interactions, Dose Prescribing Information

Jan 26, 2011 No Comments by

What is Ethamsylate (Etamsylate and Dicynene)?

Ethamsylate is a type of hemostatic agents. Ethamsylate belongs to category of hemostatic agents drugs. Ethamsylate (dicynene) is a homeostatic drug that is believed to work by increasing capillary endothelial resistance and promoting platelet adhesion. It also inhibits biosynthesis and action of those prostaglandins which cause platelet disaggregation, vasodilation and increased capillary permeability.

Indication/Contraindication for use of Ethamsylate (Etamsylate and Dicynene)

  • Hypersensitivity.
  • Prevention & treatment of capillary haemorrhages associated with (i) Haematemesis, melena, haemoptysis, haematuria, epistaxis (ii) menorrhagia, metrorrhagia, postabortion & post partum hemorrhages.

Side Effects of Ethamsylate (Etamsylate and Dicynene)

  • Transient hypotension with i injection
  • V
  • Headache, rash, nausea

Dosage and Prescribing Information for Ethamsylate (Etamsylate and Dicynene)

Adults: 250-500 mg thrice daily. Neonates: 12.5 mg/kg every 6 hrs.

Precautions while prescribing Ethamsylate (Etamsylate and Dicynene)

  • Paediatrics: Reduced dose necessary.
  • Lactation: Use with caution.
  • Safe.
  • Pregnancy: Use with caution.
  • Patients with acute porphyria.
  • Elderly.
Cardiovascular System

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