What is Doxofylline (Ansimar)?
Doxofylline is a type of enzyme inhibitor drugs that is used to treat Asthma. In animal and human studies, it has shown similar efficacy to theophylline but with significantly less side effects. Doxofylline belongs to category of enzyme inhibitor activity drugs. Specifically, Doxofylline is a new generation long acting oral methylxanthine derivative. Methylxanthines are phosphodiesterase inhibitors. Doxofylline is available as the Brand Name, Ansimar. Doxofylline also has antitussive and bronchodilator affects, and acts as a phosphodiesterase inhibitor.
For maintenance therapy in patients suffering with Asthma and Chronic Obstructive Pulmonary Disease (COPD).
Side Effects of Doxofylline (Anismar)
- No CNS and CVS side effects.
- Doxofylline has a prolonged bronchodilator effect and unlike theophylline it has least adenosine interactions.
- It is highly safe in smokers.
- There is no sleep disturbances and no effects on gastric secretions with doxofylline.
Dosages of Doxofylline (Anismar)
Adult:400mg once a day. Single dose, administration in the evening reduces nocturnal, symptoms and helps to keep the patients complaint free during the day.
However, in certain cases, 400mg twice daily is recommended on the basis of the clinical response. Doses as high as 1200mg/day (400mg 3 times day) may also be prescribed .
Precautions while using Doxofylline (Anismar)
Initial treatment of acute episodes of bronchospasm.