Diethyl Carbamazine Citrate (Banocide and Bitirazine) Side Effects, Indications, Interactions, Dose Prescribing Information

Feb 14, 2011 2 Comments by

What is Diethyl Carbamazine Citrate (Banocide and Bitirazine)?

It is the only drug available for filariasis and has a highly selective effect on microfilariae of W. bancrofti and B. malayi from peripheral blood in 7 days. Microfilariae & adult of Loa loa & Microfilariae of Onchocerca volvulus are also susceptible. It is an anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. This drug is commonly sold as Brand Name Banocide.

Indication/Contraindication for use of Diethyl Carbamazine Citrate (Banocide and Bitirazine)

  • Tropical eosinophilia.
  • Malayi, Filarial infection.
  • W
  • Pregnancy bancrofti B

Side Effects of Diethyl Carbamazine Citrate (Banocide and Bitirazine)

Nausea, joss of appetite, headache weakness, dizziness, rash, prurient, enlargement of lymph-nodes.

Dosage and Prescribing Information for Diethyl Carbamazine Citrate (Banocide and Bitirazine)

1 mg/kg body wt daily in 3 divided doses, first day,thereafter increase gradually to 6mg/kg body wt daily over 23 days after meals. Treat for 21 days.

Drug Interactions of Diethyl Carbamazine Citrate (Banocide and Bitirazine)

No known reaction.

Precautions while prescribing Diethyl Carbamazine Citrate (Banocide and Bitirazine)

  • The reaction can be minimized by starting with a low dose and give anti histaminics or corticosteroids.
  • Pregnancy: Contraindicated.
  • Lactation: Use with caution.
  • Renal impairment.
  • P may occur due to mass destruction of microfilariae and adult worms.
  • Fall in B.
  • Paediatrics: Use with caution.
Antibiotics

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2 Responses to “Diethyl Carbamazine Citrate (Banocide and Bitirazine) Side Effects, Indications, Interactions, Dose Prescribing Information”

  1. Stella says:

    I am presently treating micro filaria with banocide drug. I have rashes on my body particularly my arm and face with swelling on the sole of my feet, bottom, ankle.is it side effect of the drug, though i used to have above symtom even before using the drug.i thought this symtom ought to have disappeared with the use of banocide. I am worried. Kindly reply.thank u

  2. Stella says:

    Is rash side effect of banocide drug for treatment of filarial infection.

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