What is Nateglinide (Fastic and Starlix)? Nateglinide is a type of duplicate concept. Nateglinide belongs to category of glinide drugs. Nateglinide, which is a derivative of D phenylalanine, is a non sulfonylurea insulin secretagogue. It belongs to the meglitinide class of oral hypoglycemic agents. It causes insulin secretion via inhibition of the ATP sensitive potassium [...]

What is Repaglinide (Prandin)? It is a novel insulin secretagogue which act by lowering of post prandial blood glucose as well as fasting blood glucose in patients with type 2 diabetes mellitus by acting on the beta cells of pancreas. Repaglinide  is for the treatment of type II diabetes. It is supplied by Novo Nordisk [...]

What is Rosiglitazone (Avandia and Rosiglizole)? Rosiglitazone belongs to category of hypoglycemic agents drugs. Rosiglitazone is a type of differentiation inducer. It belongs to the thiazolidinediones group which improve insulin resistance in patients with type 2 diabetes mellitus. Rosiglitazone is an anti-diabetic drug in the triphosphopyridine class of drugs. It works as an insulin sensitizer, by binding to the [...]

What is Pioglitazone (Actos and Actost)? The active form of vitamin D. Calcitriol is formed in the kidneys or made in the laboratory. A form of vitamin D produced by the kidneys that helps the body absorbs dietary calcium into the blood and bones. Calcitriol is vitamin D3. Vitamin D is important for the absorption of [...]

What is Biguanides (Glumetza and Obimet)? They are completely different from the hypoglycaemic sulfonamides both in its structur and its mode of action. They cause little or no hypoglycaemia in nondiabetic. Possible mode of action suggested is that they interfere with mitochondrial respiratory chainspromote peripheral glucose utilization by enhancing anaerobic glycofysis or they enhance binding [...]

What is Glimepiride (Amarel and Amaryl)? It is a hypoglycaemic agent belonging to the second generation sulfonylureas. It appears to lower blood glucose by stimulating insulin release from beta cells in the pancreatic islets possibly due to increased intracellular CAMP. Glimepiride is a medium to long acting sulfonylurea anti-diabetic drug. It is marketed as Amaryl [...]

What is Glipizide (Aldiab and Digrin)? It is one of the second generation sulfonylureas, having a similar pharmacological profile, as that of G1benclamide or gliclazide. Indications  Noninsulin dependent diabetes mellitus. Glipizide is an oral drug that is used for treating patients with type 2 diabetes. It belongs to the sulfonylurea class of drugs that includes glimepiride (Amaryl), glyburide [...]

What is Gliclazide (Diamicron and Glimicron)? Gliclazide belongs to category of sulfonylurea compounds drugs. Gliclazide is a type of second generation sulfonylurea. It is a antidiabetic agent with both metabolic and vascular properties. It restores the early peak of insulin secretion and ensures glycaemic control throughout 24 hours without hypoglycaemia. Gliclazide combats microthrombosis by decreasing [...]

What is Glibenclamide (Abbenclamide and Adiab)? Glibenclamide is a type of sulfonylurea compounds. Glibenclamide belongs to category of warfarin, salicylates, sulphonamides and alcohol potentiate hypoglycaemic effect, glucocorticoids, diuretics and oestrogen reduce hypoglycaemic effect, synergistic hypglycaemic action with metformin. drugs. Single dose provoke a brisk release of insulin from pancreas. It acts on Beta cell membrane [...]

What is Tolbutamide (Aglicid and Apo-Tolbutamide)? Tolbutamide is a type of sulfonylurea compounds. Tolbutamide belongs to category of hypoglycaemic effect enhanced by dicoumarol, clofibrate, chloramphenicol & amp cyclophosphamide & amp effect reduced by corticosteroids, adrenaline, oral contraceptives & amp thiazide drugs. It is classified as first generation sulfonylurea sole significant action being low ering of blood [...]