Endocrine

Letrozole (Femara, Nonsteroidal Aromatase Inhibitor), Indication, Side Effects, Dosage

Dec 19, 2010 No Comments by Julie K

What is Letrozole (Femara)? Letrozole belongs to category of hormonal drugs. It is a nonsteroidal aromatase inhibitor and is considered alternative to tamoxifen for the treatment of advanced, post menopausal breast cancer. Letrozole prevents the aromatase from producing estrogens. The action is specific, and letrozole does not reduce production of mineralo- or corticosteroids. In contrast, Tamoxifen interferes [...]

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Anastrozole (Arimidex) Non Steroidal Aromatase Inhibitor

Dec 19, 2010 No Comments by Josh

What is Anastrozole (Arimidex)? Anastrozole is a new generation nonsteroidal aromatase inhibitor, which selectively and potently blocks the enzymatic synthesis of estrogen from androgen. It is sold under the brand name Arimidex by Astra Zeneca. Indication/Contraindication for use of Anastrozole (Arimidex) Anastrozole is used alone or with other treatments, such as surgery or radiation, to [...]

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Raloxifene (Evista) Indications, Side Effects, Prescribing Dosage

Dec 19, 2010 No Comments by Kristen M

What is Raloxifene (Evista)? Raloxifene is a type of selective estrogen receptor modulators. It is a Selective Estrogen Receptor Modulator (SERM), a new form of antiresorptive therapy that reduces the risks of osteroporosis and also improves the cardiovascular profile in postmenopausal women. It is sold under the brand name Evista. Indication/Contraindication for use of Raloxifene (Evista) [...]

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Ormeloxifene (Saheli, Centchroman) Indications, Side Effects and Prescribing Information

Dec 19, 2010 No Comments

What is Ormeloxifene (Saheli, Centchroman)? It belongs to the new category of agents called as Selective Estrogen Receptor Modulators (SERMs). It has a weak estrogenic and a potent antiestrogenic profile. It is expected to exert a contraceptive effect and normalize the bleeding from uterine cavity by regularizing the expression of estrogen receptors on the endometrium, [...]

Calcitonin Salmon (Miacalcin) Side Effects, Dosage, Interaction Information

Dec 18, 2010 No Comments

What is Calcitonin Salmon (Miacalcin)? Calcitonin is a 32 -amino acid hormone produced in the thyroid gland and influences calcium metabolism. It counteracts the effects of the para-thyroid hormone thus maintaining calcium hemostasis. Salmon calcitonin is a synthetic polypeptide of 32 amino acids in the same linear sequence that is found in calcitonin of salmon [...]

Saxagliptin (Onglyza, and DPP-IV Inhibitor) Side Effects, Indications, Interactions, Dose Prescribing Information

Dec 18, 2010 2 Comments

What is Saxagliptin (Onglyza)? Saxagliptin (brand name Onglyza) is a selective, reversible inhibitor of DPP-4 (Di-peptidyl Transferase), a key enzyme that regulates the incretin effect (in which the hormones in the stomach influence insulin secretion in response to rise in blood sugar after a meal). Saxagliptin, is a newer agent in the class of DPP-IV [...]

Miglitol (Glyset) Treatment For Type 2 Diabetes (side effects, dosage)

Dec 13, 2010 1 Comment

What is Miglitol (Glyset)? Miglitol is a type of alpha-glucoside inhibitor. Miglitol is similar in action to acarbose. It is an oral anti-diabetic drug that acts by inhibiting the ability of the patient to breakdown complex carbohydrates into glucose. Miglitol is an oral anti-diabetic drug that acts by inhibiting the ability of the patient to breakdown [...]

Alogliptin Benzoate (SYR-322) Side Effects, Indications, Interactions, Dosage Information

Nov 30, 2010 3 Comments

What is Alogliptin (SYR-322)? Alogliptin Benzoate is a Dipeptidyl Peptidase-IV inhibitors (DPP-IV) inhibitor currently in phase III clinical trials for treatment of Type 2 Diabetes Mellitus. However, at this time, the FDA has requested the manufacturer, Takeda Pharmaceutical to submit additional data about the cardiovascular safety of the drug (concerns of cardiovascular adverse events of anti-diabetes [...]