Bisoprolol (Cardicor and Concor) Side Effects, Indications, Interactions, Dose Prescribing Information

Jan 20, 2011 2 Comments by

What is Bisoprolol (Cardicor and Concor)?

Bisoprolol belongs to category of beta 1 blocking agent drugs. Bisoprolol is a type of adrenergic beta-antagonists.

It is a competitive antagonist of the betaadrenergic receptors. It has high beta, selectivity. There is no membranestabilising or partial agonist action. Reduction in heart rate and blood pressure. Action lasts for 24 hrs. Bisoprolol is a drug belonging to the group of beta blockers, a class of drugs used primarily in cardiovascular diseases. More specifically, it is a selective type β1 adrenergic receptor blocker.

This drug is commonly sold as Brand Name Cardicor.

Indication/Contraindication for use of Bisoprolol (Cardicor and Concor)

  • Hypertension, Coronary artery disease.
  • Bradycardia, second or third degree heart block, conduction abnormalities, congestive heart failure, chronic obstructive pulmonary disease, peripheral vascular insufficiency, pregnancy and lactation.

Side Effects of Bisoprolol (Cardicor and Concor)

Giddiness, headache, fatigue, bradycardia, nausea, dyspnoea, sleep disturbances, cold extremities, reduced libido.

Dosage and Prescribing Information for Bisoprolol (Cardicor and Concor)

Start at 2.5 or 5mg/day and build up to10 20mg/day.Dose reduction in severe renal impairment.

Drug Interactions of Bisoprolol (Cardicor and Concor)

Enhances the action of anaes thetic agents, clonidine, calcium antagonists, hypoglycaemic agents & NSAIDs. Rifampicin cause reduction in plasma concentration & elimination halflife of drug.

Precautions while prescribing Bisoprolol (Cardicor and Concor)

  • Elderly: Use with caution.
  • V function, bronchial asthma, diabetes, thyrotoxicosis, M.
  • Pregnancy: Safety not established.
  • I, severe renal impairment, abrupt withdrawal.
  • Paediatrics: Not recommended.
  • Lactation: Use with caution.
  • Poor L..
Cardiovascular System

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2 Responses to “Bisoprolol (Cardicor and Concor) Side Effects, Indications, Interactions, Dose Prescribing Information”

  1. Yasmin says:

    My mom (62) has switched to concor + norvask (5mg each) about a week ago
    And this morning she suffered from vertigo and lower than usual Bp 112/55 , and still has not recovered, coud this be q side effect?

    • conadmin says:

      Hi Yasmin.

      Concor( bisoprolol) has moderate interactions with amlodipine(norvasc, which is a calcimum channel blocker). This interaction can result in the slowing in heart rate, cardiac muscual contractions and conduction particularly in patient’s with ventricular or conduction abnormalities. Also, calcium channel blockers like norvasc inhibit CYO450 metabolism of betablockers like Concor, resulting in increased serum concentrations of this drug.

      In short – we wold strongly recommend that you onsult a cardiologist for examination and further information on use of these drugs together.

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