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Showing 1 to 10 of total 140 Prostate Cancer clinical trials
Enzalutamide in Combination With PSA-TRICOM in Patients With Non-Metastatic Castration Sensitive Prostate Cancer
Background: - Enzalutamide is a well tolerated hormone therapy that is used to treat advanced prostate cancer. It is given to help kill cancer cells and limit cancer cell growth. ...
Phase
Interventional
Research Sites:1
NA
Rituximab Neoadjuvant Therapy in Patients With Prostate Cancer Scheduled to Undergo Radical Prostatectomy
There is now substantial evidence that B cells are recruited into prostate cancers by CXCL13 released by the tumor cells. B cells release lymphotoxin which drives malignant cell proliferation through ...
Phase NA
Interventional
Research Sites:1
NA
A Study of the Safety and Pharmacokinetics of Escalating Doses of DSTP3086S in Patients With ...
This is a Phase I, multicenter, open-label, dose-escalation study of DSTP3086S administered as a single agent by intravenous (IV) infusion to patients with metastatic Castration-Resistant Prostate Cancer (CRPC).
Phase
Interventional
Research Sites:5
NA
Study of GDC-0068 Or GDC-0980 With Abiraterone Acetate Versus Abiraterone Acetate in Patients With Castration-Resistant ...
This multicenter, international, Phase Ib/II trial consists of two stages: a Phase Ib, open-label stage in which the recommended Phase II dose will be determined for GDC-0068 and GDC-0980 in ...
Phase
Interventional
Research Sites:4
NA
Saw Palmetto: Symptom Management for Men During Radiation Therapy
The aim of this study is to test whether Saw Palmetto, is useful in preventing or reducing the side effects for men undergoing radiation therapy for prostate cancer. Urinary symptoms ...
Phase NA
Interventional
Research Sites:4
NA
Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer
RATIONALE: Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells and shrink tumors. Androgens can cause the growth of prostate cancer cells. Androgen-deprivation therapy may ...
Phase
Interventional
Research Sites:246
NA
Hypofractionated Stereotactic Body Radiation Therapy as a Boost to the Prostate
In this study, participants will have standard androgen deprivation therapy and undergo standard radiation therapy to the prostate and at-risk lymph nodes by intensity-modulated radiation therapy (IMRT). The subsequent *boost* ...
Phase
Interventional
Research Sites:1
NA
Resistance Training and Whey Protein Supplementation in Increasing Lean Body Mass in Patients With Prostate ...
This randomized pilot clinical trial studies resistance training and whey protein supplementation in increasing lean body mass in patients with prostate cancer receiving androgen deprivation therapy. Resistance training and whey ...
Phase NA
Interventional
Research Sites:1
NA
A Phase 1 Study of MLN8237 in Patients With Advanced Solid Tumors Including Castration-Resistant Prostate ...
This is an open-label, multicenter, Phase 1 study that will evaluate the safety and tolerability of MLN8237 given orally in combination with docetaxel as a treatment for advanced solid tumors ...
Phase
Interventional
Research Sites:1
NA
Trial of ADI-PEG 20 Plus Docetaxel in Solid Tumors With Emphasis on Prostate Cancer
This Phase I trial combines ADI-PEG 20 with docetaxel in patients with advanced solid tumors with emphasis on castration resistant prostate cancer (CRPC). The investigators hypothesize that the combination will ...
Phase
Interventional
Research Sites:1
NA
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