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Showing 1 to 10 of total 425 diabetes clinical trials
A Study of the Safety and Efficacy of MK-3102 Compared With Glimepiride in Participants With ...
This trial will assess the safety and efficacy of MK-3102 compared with the sulfonylurea, glimepiride, in Type 2 diabetes mellitus participants with inadequate glycemic control on metformin monotherapy.
Phase
Interventional
Research Sites:1
NA
Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Engerix -B in Adults With or Without ...
This study will evaluate the immunogenicity and safety of Engerix™-B (hepatitis B vaccine) when administered as a primary vaccination course at 0, 1 and 6 months in adults with or ...
Phase
Interventional
Research Sites:9
Accepts Healthy Volunteers
Phase 2b Multicenter Randomized Double-Blind Placebo- and Active-Controlled Parallel-Group Study to Assess the PD Response ...
Primary objective: The primary objective of this study is to define the dose response of Glymera as measured as the change from baseline in hemoglobin A1c (HbA1c) following 20 weeks ...
Phase
Interventional
Research Sites:69
NA
Comparison of a New Formulation of Insulin Glargine With Lantus in Patients With Type 1 ...
Primary Objective: - To compare the glucose control during treatment with a new formulation of insulin glargine and Lantus in adult patients with type 1 diabetes mellitus Secondary Objectives: - ...
Phase
Interventional
Research Sites:3
NA
Point-of-Care Glucose Testing and Insulin Supplementation
Capillary point-of-care (POC) testing is advocated as a valuable aid in the management of diabetes and hyperglycemia in the hospital setting. POC testing aims at collecting information on BG levels ...
Phase NA
Interventional
Research Sites:2
NA
Comparison of a New Formulation of Insulin Glargine With Lantus in Patients With Type 2 ...
Primary Objective: To compare the efficacy of a new formulation of insulin glargine and Lantus in terms of change of HbA1c from baseline to endpoint (scheduled at month 6, week ...
Phase
Interventional
Research Sites:9
NA
Study of Sitagliptin for the Treatment of Type 2 Diabetes Mellitus With Inadequate Glycemic Control ...
The purpose of this study is to examine the insulin-sparing effect of sitagliptin 100 mg once-daily compared with placebo over 24 weeks in participants with type 2 diabetes mellitus who ...
Phase
Interventional
Research Sites:28
NA
Safety Tolerability Pharmacokinetics and Pharmacodynamics of MK-8655 in Participants With Type 2 Diabetes (MK-8655-002 AM1)
This study will assess the initial safety, tolerability, pharmacokinetics, and pharmacodynamics of MK-8655, after single and multiple daily oral administrations to participants with Type 2 Diabetes (T2DM). The study will ...
Phase
Interventional
Research Sites:1
NA
Barriers to Physical Activity in People With Type 2 Diabetes
The investigators plan to learn more about how different levels of exercise feel to people with Type 2 Diabetes and how it feels to people without Type 2 Diabetes. This ...
Phase NA
Interventional
Research Sites:1
Accepts Healthy Volunteers
Effects of Glimepiride on Recovery From Hypoglycemia in Participants With Type 2 Diabetes Mellitus (MK-0000-253)
This study aims to assess how glimepiride affects the recovery from hypoglycemia in participants with type 2 diabetes mellitus.
Phase
Interventional
Research Sites:1
NA
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