Recently, I came across an article in MedicineNet.com which states that glioma is a rare type of tumor that starts from glial cells. The glial cells act as the connective tissue of the central nervous system. This tumor originates in the brain or spinal cord and other nerves such as the optic nerve. The most common site of gliomas is the brain. Brain tumors are classified as primary or secondary tumors. Gliomas are primary brain tumors that can be slow-growing (benign) or fast growing (malignant).
Glioma is the most common and most serious form of brain tumors that affect adults. There are many types of gliomas. The type of glioma is determined by the cells that give rise to the tumor. Astrocytoma, oligodendroglioma, glioblastoma, oligoastrocytoma are all examples of gliomas.
Signs and Symptoms of Glioma
Following are some signs and symptoms of Glioma:
• Vision problems
• Pain, Weakness
• Personality changes
• Paralysis on one side of body
• Memory problems
• Fatigue or increased sleep
Glioma Prognosis/ Life Expectancy
Gliomas cannot be cured. The prognosis of gGlioma refers to the outcome of glioma. The prognosis of glioma may include duration of glioma, chances of complications of glioma, probable outcomes, prospects for recovery, recovery period for glioma, survival rates, death rates and other possibilities in the overall prognosis of glioma. Gliomas can be low grade cancer tumours with a relatively long life expectancy. A low-grade oligodendroglioma patient has an average survival of 11.6 years. High grade gliomas are also called gliobastoma multiforme (GBM). These are very aggressive tumours with a poor prognosis. A patient with glioblastoma multiforme has an average survival of only 12 months.
Listed below are some clinical trials investigating new treatments for Glioma.
- Treating Patients With High-Grade Glioma With IA Carboplatin-based Chemotherapy With or Without Sodium Thiosulfate
- Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic Astrocytoma
- A Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain Tumors
- Study of the Poly (ADP-ribose) Polymerase-1 (PARP-1) Inhibitor BSI-201 in Patients With Newly Diagnosed Malignant Glioma