People with Schizoaffective Disorder may have an imbalance of certain chemicals in the brain which are also known as Neurotransmitters that help nerve cells in the brain to send messages to each other. An imbalance in these chemicals can interfere with the transmission of messages which can lead to psychotic symptoms.

The person affected by Schizoaffective disorder sometimes hear voices and sees things which are actually not present
These psychotic symptoms affect the mind of the sufferer badly
- Depression – It is that condition in which people have to suffer with depressive symptoms. It makes a person feel sad, bored and tired. If the depression gets really bad, then it makes a person feel alone while having many people around. In this situation a person have to go through with many health problems like
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- Poor appetite
- Weight loss or gain
- Changes in sleeping patterns
- Agitation (excessive restlessness)
- Lack of energy
- Loss of interest in usual activities
- Feelings of worthlessness or hopelessness
- Guilt or self-blame
- Inability to think or concentrate
- Thoughts of death or suicide
- Mania – It is that condition which makes a person feel very excited and enthusiastic about life, talkative, and with your head jumping with thoughts, ideas and plans. The problems related to this condition are
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- Increased activity, including work, social, and sexual activity
- Speaking so fast that others can’t understand or interrupt
- Strange or Unusual Thoughts
- Problem in sleep
- Agitation
- Inflated self-esteem
- Distractibility
- Self-destructive or dangerous behavior
- Hallucinations – It is that condition which makes a person hear, see, smell or feel something when they are actually not. The voices might give commands, make comments about the person’s behavior, or warn that something awful is about to happen. It can lead to very serious problems like
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- Feeling a crawling sensation on the skin
- Hearing voices when no one has spoken
- Seeing patterns, lights, beings, or objects that aren’t there
- Delusions – It is that condition which makes a person having unusual, illogical or false beliefs. People with these symptoms can also have thoughts that others are cheating or someone is trying to harm them. In this state of mind people suffering with Schizoaffective Disorder is far more likely to hurt themselves than anybody else.
- Dissociation - It is that condition which produces a lack of connection in a person’s thoughts, memories, feelings, actions, or sense of identity.
According to doctors, hallucinations and delusions are most common psychotic symptoms because in these situations a person reacts differently from reality. These problems can be very dangerous for people.
Listed below are some clinical trials investigating new treatments for Schizoaffective Disorder.
- Augmenting Zyprexa With Naltrexone to Ameliorate Metabolic Side-Effects
- Effects of Modafinil on Brain Function in Patients With Schizophrenia
- Modafinil for Treatment of Cognitive Dysfunction in Schizophrenia
- A Study of Varenicline for Prevention of Relapse to Smoking in Patients With Schizophrenia or Bipolar Disorder
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