Pulmonary Fibrosis is referred to the condition described as scarring of lungs. In this condition, an excessive amount of fibrous connective tissues develop in the lungs. As a result of this the lungs cannot function to their capacity.
There are quite a few causes of Pulmonary Fibrosis. It can occur as a secondary development of some other disease like viral infections, autoimmune disorders and microscopic injuries. However, it can also occur without any significant cause. Certain risk factors for Pulmonary Fibrosis are – inhaling pollutant substances like silica, asbestos and harmful gases, exposure to ionizing radiation and chronic health conditions like rheumatoid arthritis.
Symptoms of Pulmonary Fibrosis are usually trouble in breathing, fatigue, weakness, discomfort feeling in chest, unexplained coughing, loss of appetite and sudden loss of weight. Lung biopsy is the most effective method to confirm Pulmonary Fibrosis. In addition to this, chest X-ray and chest CT scan can also provide helpful information for diagnosis.
Treatment of Pulmonary Fibrosis is very critical as the only option is a lungs transplant. There is no medication or procedures wthat can stop or control the growth. Certain corticosteroid medications have been proved to be effective in controlling the inflammation and development of new scars. However, these medicines are not suitable for everyone, as there are many risks associated to steroid medication.
Development of most effective treatment method for Pulmonary Fibrosis has come to be most necessary at this point. There are currently 40 different interventions being investigated in Pulmonary Fibrosis clinical trials. These clinical trials are being conducted in 75 cities and are being performed by 123 different clinical trial investigators (doctors who conduct and supervise the clinical study). There are 44 Pulmonary Fibrosis trials currently active in the United States. A total of 1 Phase I, 8 Phase II and 9 Phase III clinical trials are currently active for Pulmonary Fibrosis (the phases represent the different stage in the development of a treatment for a given condition. Learn more about what the different phases of a clinical trial mean and how they differ).
Pulmonary Fibrosis clinical trials interventions
- Pulmonary Rehabilitation
- Bibf 1120
- Inhaled Nitric Oxide
- Mycophenolate Mofetil
Sites/Medical Centers doing Pulmonary Fibrosis Clinical Trials
- Columbia University Medical Center
- Yale University School of Medicine
- The University of North Carolina at Chapel Hill
- Duke University Medical Center
- Medical University of South Carolina
- National Institute of Neurological Disorders and Stroke (NINDS), 9000 Rockville
- Vanderbilt University
- The University of Arizona
- National Jewish Health
- Mayo Clinic
- Temple University
- University of Pittsburgh
Clinical Trial Investigators for Pulmonary Fibrosis
- David J Lederer, M.D. (Columbia University Medical Center)
- Danielle Antin-Ozerkis, MD (Yale University School of Medicine)
- Michael R Knowles, MD (The University of North Carolina at Chapel Hill)
- Will Simmons, MS, CCRP (Duke University Medical Center)
- Richard M Silver, MD (Medical University of South Carolina)
- Patient Recruitment and Public Liaison Office (National Institute of Neurological Disorders and Stroke (NINDS), 9000 Rockville)
- Lisa Lancaster, MD (Vanderbilt University)
- Gordon Carr (The University of Arizona)
- Aryeh Fischer, MD (National Jewish Health)
- Steven R. Ytterberg, MD (Mayo Clinic)
- Gerard Criner, M.D. (Temple University)
- Kevin F. Gibson, M.D. (University of Pittsburgh)
List of Clinical Trials for Pulmonary Fibrosis
- Evaluation of the Causes and Disease Processes of Chronic Lung Disease
- Studying Patients With Cystic Fibrosis and Other Pulmonary and Pancreatic Disorders
- Immune Regulation in Patients With Common Variable Immunodeficiency and Related Syndromes
- Study and Treatment of Inflammatory Muscle Diseases
If you or your friend or family has pulmonary fibrosis, then you may want to find a clinical trial. You can use the pulmonary fibrosis clinical trials tool to find a medical study near you.