List of Hodgkin’s Lymphoma Clinical Trials, New Treatments

Stained Microslide Showing Hodgkins Lymphoma CellsStained Image of Hodgkins Cells. Source: Wikimedia.org

Hodgkin Lymphoma is the cancer of immune system affecting lymphocytes or white blood cells in the human body. The disease is named after Thomas Hodgkin, who was the first to notice this lymphatic abnormality in the year 1832. Hodgkin’s Lymphoma is identified by marking the presence of Reed-Sternberg type cell. Two main types of Hodgkin Lymphoma have been noticed in human, which are classical Hodgkin Lymphoma and nodular lymphocyte-predominant Hodgkin Lymphoma.

The most prominent symptom of Hodgkin’s Lymphoma is the swollen lymph nodes, spleen and other tissues related to the body immune system. Normally there is no pain associated with the enlargement. However, it might include fever, fatigue, drastic loss of body weight, sweating at night etc.

The diagnostic procedure for Hodgkin’s Lymphoma is almost similar as it is for any other cancer. Patient has to go through diagnostic tests like biopsy, CT scan, PET scan, MRI etc. Depending on the stage of cancer, treatment decision is considered. Usually three types of treatment procedures are used, which are chemotherapy, radiation therapy and surgery. Hodgkin’s Lymphoma for pregnant women might require different treatment procedures like close monitoring and steroid therapy.

New treatments are being tested by medical scientists to treat Hodgkin’s  Lymphoma. Clinical trials for Hodgkin’s Lymphoma are an important step in the development of new treatments. There are approximately 50 Hodgkin’s Lymphoma trials currently active in the United States. Of these 7 clinical trials are in Phase I, 21 are in Phase II and 2 are in Phase III (read more about <a href=”http://trialx.com/curetalk/2010/11/what-are-the-phases-of-clinical-trial/”>what the different phases of a clinical trial mean and how they differ</a>). These clinical trials are being performed and managed in 62 cities by 75 different clinical trial investigators. Listed below are some of these interventions, new treatments under investigation, research investigators and clinical trials

Hodgkin Lymphoma clinical trials interventions

  • Laboratory Biomarker Analysis
  • Etoposide
  • Cyclophosphamide
  • Mycophenolate Mofetil
  • Peripheral Blood Stem Cell Transplantation
  • Fludarabine Phosphate
  • Tacrolimus
  • Total-Body Irradiation
  • Flow Cytometry
  • Melphalan
  • Cyclosporine
  • Rituximab

Sites/Medical Centers doing Hodgkin Lymphoma Clinical Trials

  • Penn State Milton S Hershey Medical Center
  • Colorado Blood Cancer Institute
  • Penn State Milton S Hershey Medical Center
  • Beth Israel Deaconess Medical Center
  • Virginia Commonwealth University
  • Blood & Marrow Transplant Program at Northside Hospital
  • Northwestern University, The Robert H Lurie Comprehensive Cancer Center
  • Ohio State University Medical Center
  • University of Kansas Medical Center
  • University of Rochester Medical Center
  • Illinois CancerCare-Peoria
  • Dana-Farber Harvard Cancer Center

Clinical Trial Investigators for Hodgkin Lymphoma

  • John M. Varlotto (Penn State Milton S Hershey Medical Center)
  • Jeffrey Matous, MD (Colorado Blood Cancer Institute)
  • John M. Varlotto (Penn State Milton S Hershey Medical Center)
  • David Avigan, MD (Beth Israel Deaconess Medical Center)
  • John McCarty, MD (Virginia Commonwealth University)
  • Scott Solomon, MD (Blood & Marrow Transplant Program at Northside Hospital)
  • Leo Gordon, MD (Northwestern University, The Robert H Lurie Comprehensive Cancer Center)
  • Maryam B. Lustberg (Ohio State University Medical Center)
  • Joseph McGuirk, DO (University of Kansas Medical Center)
  • Jonathan Friedberg, MD (University of Rochester Medical Center)
  • James A. Knost (Illinois CancerCare-Peoria)
  • Amy Billett, MD (Dana-Farber Harvard Cancer Center)

List of Clinical Trials for Hodgkin Lymphoma

If you are interested in participating in a clinical trial of hodgkin lymphoma, you can find trials near you.

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