List of Gastroparesis Clinical Trials

Gastroparesis is a disease of the stomach, in which the stomach is unable to empty out its contents fully or partially. In case of Gastroparesis, the failure of stomach functionality is not caused by any obstruction in the digestive system.

Exactly what causes Gastroparesis, is not well understood till now. However, scientists consider this to develop because of  a disruption of neural signals to the stomach. Often it is noticed in patients with Diabetes Mellitus. Persons with Systemic Sclerosis and Gastrectomy also have a higher risk of Gastroparesis. It can also occur as an after effect of certain nerve signal blocking medication.

Symptoms of Gastroparesis includes nausea, abdominal fullness, vomiting, loss of weight, abdominal distention etc. For diabetic patients, Gastroparesis can cause Hypoglycemia.

Diagnosis is mainly done through tests like Esophagogastroduodenoscopy or EGD, gastric emptying studies etc. Treatment of Gastroparesis involves medications and diet restrictions. Small and well cooked meals are prescribed for patients. For patients with Diabetes Mellitus, it is highly recommended to keep the blood sugar level in control, because it might improve the symptoms of Gastroparesis. Botox treatment and surgery are also used at certain situations.

Several research studies are being conducted by experts to find out effective treatment for Gastroparesis. Clinical trials for Gastroparesis are an important step in the development of new treatments and 19 clinical trials are currently active in the United State for gastroparesis. There are currently 19 different interventions being investigated in Gastroparesis clinical trials. Of the 19 Gastroparesis clinical trials (medical research studies), 1 clinical trials are in Phase I, 5 are in Phase II and 2 are in Phase III (read more about <a href=”http://trialx.com/curetalk/2010/11/what-are-the-phases-of-clinical-trial/”>what the different phases of a clinical trial mean and how they differ</a>). These clinical trials are being conducted in 65 cities and are being performed by 75 different clinical trial investigators (doctors who conduct and supervise the clinical study).

Gastroparesis clinical trials interventions

  • Domperidone
  • Hemin
  • Hemin
  • Albumin (25%)
  • Erythromycin
  • Sapropterin Dihydrochloride
  • Azithromycin
  • Rm-131
  • Tadalafil
  • Continuous Glucose Monitoring System And Insulin Pump
  • Nortriptyline Hydrochloride
  • Nortriptyline-Placebo

Sites/Medical Centers doing Gastroparesis Clinical Trials

  • Stanford University School of Medicine
  • University of Michigan Medical Center
  • Mayo Clinic
  • Allegiance Gastroenterology
  • University of Florida
  • University of Mississippi Medical Center
  • Texas Tech University Health Sciences Center
  • Gail and Gerald Oppenheimer Family Center for Neurobiology of Stress
  • Texas Tech University Health Sciences Center
  • Wake Forest University Health Sciences
  • University of Kansas Medical Center (KUMC)
  • University of Michigan Medical Center

Clinical Trial Investigators for Gastroparesis

  • Richard W McCallum, MD (University of Kansas Medical Center (KUMC))
  • William L Hasler, MD (University of Michigan Medical Center)
  • Henry P. Parkman, MD (Temple University School of Medicine)
  • Richard W McCallum, MD (Texas Tech University Health Sciences Center)
  • Kenneth L Koch, MD (Wake Forest University Health Sciences)
  • Micki Suits, RN (Carle Health Care Incorporated d/b/a Carle Physician Group)
  • William Snape, MD (California Pacific Medical Center)
  • US GSK Clinical Trials Call Center (GSK Investigational Site)
  • Shahnaz Sultan, MD (University of Florida)
  • Pankaj J Pasricha, MD (Stanford University)
  • George L Arnold, MD (UPMC Shadyside Hospital)
  • Pankaj Jay Pasricha (Stanford University School of Medicine)

List of Clinical Trials for Gastroparesis

If you are interested in participating in a clinical trial of gastroparesis, you can find trials near you.

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  • gloria

    Hi i was wondering if you know of any trials for gastroparesis in or close to new zealand? My 24 yo daughter is very ill and we were looking at a gastric pacemaker or botox injections or something to give her releif/ shbe has has a bit of releif with mirtazapine after domperidone etc did not work but has recently relapsed and is on afeed tube again, She cannot liveliuke this is there any hope for some help?

  • Amber Ferguson

    Hi, my name is Amber. I have been diagnosed with severe gastroparesis and I’m trying to find any help I can get. If that means doing a clinical study then I am absolutely up for that. I have been dealing with this for almost 25 years. This condition has taken over my life and I’m desperate to find any relief! I have been on so many medications, I have done every test out there and my doctors tell me there is nothing more they can do :( Besides the dietary change, smaller portion sizes and exercise, is there anything more I can do? Like many of us who suffer from this crippling condition, I just want to have a day where I can feel alive and not a prisoner in my home and body! Thank you soOoOOo much for the advice and help :)

  • aura

    I am doing a 6th grade project on the Stomach, it’s diseases and I was wondering if you can post some things about Gastroparesis? Like:
    Famous people with it
    About it’s effects to people
    and about it?
    Thanks youu