List of Chronic Myelomonocytic Leukemia (CMML) Clinical Research Studies, New Treatments and Research Sites

Chronic Myelomonocytic Leukemia or CMML is a type of rare bone marrow malignancy. This particular type of leukemia affects two types of blood cells, myelocytes and monocytes. The causes of Chronic Myelomonocytic Leukemia can be genetic or a combination of viruses and or exposure to harmful chemicals and radiation.

The symptoms of Chronic Myelomonocytic Leukemia normally includes acute anemia, dizziness, fever, respiratory problem, uncontrolled bleeding, easy bruising, fatigue, bone pain, headache, loss of body weight and so on.

Diagnosis of Chronic Myelomonocytic Leukemia is mainly done with specific blood tests. The treatment depends on the stage of the disease. Chemotherapy is the most common way to treat Chronic Myelomonocytic Leukemia. However, stem cell transplant can also be used to treat the patient for Chronic Myelomonocytic Leukemia.

New developments are underway because of the effort of medical scientists and clinical research professionals. Clinical trials for Chronic Myelomonocytic Leukemia are an important step in the development of new treatments and 18 clinical trials are currently active in the United State for Chronic Myelomonocytic Leukemia. These  Chronic Myelomonocytic Leukemia clinical trials are being performed and managed in 20 cities by 25 different clinical trial investigators. There are currently 49 different interventions (i.e., drugs, procedures etc) being investigated in Chronic Myelomonocytic Leukemia clinical trials.

I have provided a short list of some of the Interventions under investigation, the research sites conducting the clinical trials and the list of the trials themselves. If you or your friend or family has Chronic Myelomonocytic Leukemia, then you may want to find a chronic myelomonocytic leukemia clinical trial near you.

Chronic Myelomonocytic Leukemia clinical trials interventions

  • Laboratory Biomarker Analysis
  • Mycophenolate Mofetil
  • Flow Cytometry
  • Cyclosporine
  • Total-Body Irradiation
  • Fludarabine Phosphate
  • Peripheral Blood Stem Cell Transplantation
  • Allogeneic Hematopoietic Stem Cell Transplantation
  • Cyclophosphamide
  • Cytogenetic Analysis
  • Clofarabine
  • Tacrolimus

Sites/Medical Centers doing Chronic Myelomonocytic Leukemia Clinical Trials

  • Hem Onc Assoc of South Texas
  • Robert H. Lurie Comprehensive Cancer Center at Northwestern University
  • Covance Research Unit, Inc
  • St James Hospital - Department of Haematology
  • Colorado Blood Cancer Institute
  • Wake Forest University Health Sciences
  • Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
  • North Star Lodge Cancer Center
  • Johns Hopkins University
  • Ireland Cancer Center at University Hosptials Case Medical Center, Case Comprehensive Cancer Center
  • Cancer Centers of Florida
  • University of Utah

Clinical Trial Investigators for Chronic Myelomonocytic Leukemia

  • Joanne Hardy (Hem Onc Assoc of South Texas)
  • Clinical Trials Office - Robert H. Lurie Comprehensive Cancer (Robert H. Lurie Comprehensive Cancer Center at Northwestern University)
  • Associate Director, Clinical Trial Disclosure (Covance Research Unit, Inc)
  • Kristi Whiteside, BS, MPA (St James Hospital - Department of Haematology)
  • Michael B. Maris (Colorado Blood Cancer Institute)
  • Alexandra Bo Allen (Wake Forest University Health Sciences)
  • Brenda Cooper, MD (Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center)
  • Thomas Boyd, MD (North Star Lodge Cancer Center)
  • Christine L. Hann (Johns Hopkins University)
  • Brenda Wi Cooper (Ireland Cancer Center at University Hosptials Case Medical Center, Case Comprehensive Cancer Center)
  • Carlos Alemany, MD (Cancer Centers of Florida)
  • Brandon Rodriguez (University of Utah)

List of Clinical Trials for Chronic Myelomonocytic Leukemia

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  • http://questions? Mark

    Hi, I have CMML and am a 53 yr old male. I was diagnosed in April of 2009 and have gone through 6 months of Vidaza chemo-thereapy. My father, who is 78 was diagnosed with CMML just his year. also.

    I am experiencing bone and muscle pain that my drs. say is not normal. I have chronic skin infections, sores that the culture showed was staph, mostly on my face, arms, legs and thighs. My calfs swell up monthly, get hot and a red rash on them. My shoulders and wrists ache. Is this normal?


    • Emilia.Cure

      Hello Mark,

      Thanks for your comment. Regarding the symptoms you are experiencing, is definitely not normal. I think you should contact your physician to find a correct treatment for these problems.

      Best wishes.


  • Lorrie

    Hi. My dad is 84 and was just diagnosed with CMML. He will be starting his injections soon. Is CMML hereditary? Three years ago he had C. Difficile after a surgery and had a white cell count of 70,000 (yes, that is the correct number). Really, it is a miracle he survived! I am wondering if he had CMML then and had just not been diagnosed yet.