The goal of this study is to compare the time required for accurate heart rate measurement of the preterm newborn when using pulse oximetry versus electrocardiography leads. Clinical Trial Conditions: Prematurity Treatments in this Clinical Trial : Apparatuses Eligible Clinical Trial Participant Age : Between 0 years to 1 years Can Healthy Volunteers Participate: No [...]
To assess if the sublingual tablet will have similar pharmacokinetics as the conventional tablet of alprazolam. Clinical Trial Conditions: Anxiety Disorder Treatments in this Clinical Trial : Alprazolam tablet, Alprazolam sublingual Clinical Trial Phase: Phase 1 Eligible Clinical Trial Participant Age : Between 18 years to 55 years Can Healthy Volunteers Participate: Yes Clinical Trial [...]
The investigators purpose is to prospectively characterize influenza infections over a 3 year period in transplant patients using a registry system. The investigators plan to generate robust data on clinical features of upper and lower respiratory disease, antiviral therapy and its effects on disease outcome, as well as quantitative virologic data on shedding and antiviral [...]
The aim of the study is to compare rapamycin eluting stent and paclitaxel eluting balloon catheter in the treatment of restenosis in bare metal stent. Clinical Trial Conditions: In-Stent Restenosis Treatments in this Clinical Trial : Rapamycin eluting stent implantation, Paclitaxel eluting balloon catheter Clinical Trial Phase: Phase 3 Eligible Clinical Trial Participant Age : [...]
This study will assess the impact of the systematic detection by rapid diagnostic test (RDT) and treatment of asymptomatic carriers of malaria parasites (P. falciparum) with AL (or AL dispersible) on the number of clinical malaria cases in children less than 5 years of age and the improvement of hemoglobin levels in the overall population. [...]
The purpose of this study is to characterize the safety and hemostatic activity of topical Fibrocaps in surgical patients when control of mild to moderate bleeding by standard surgical techniques is ineffective and/or impractical. Clinical Trial Conditions: Mild to Moderate Bleeding Treatments in this Clinical Trial : Fibrocaps (fibrin sealant), Gelfoam Clinical Trial Phase: Phase [...]
The purpose of this trial is the generation of clinical data required for a 510(k) submission to the FDA. The trial design reflects elements desired by the FDA. The trial is designed to satisfy the relevant requirements of the FDA Guidance (March 1993) on the content of premarket notification [510(k)] submissions for clinical electronic thermometers [...]
A multi-center, prospective, randomized, single-blind, controlled, comparative efficacy and safety trial in subjects undergoing open liver resection surgery. The study will enroll 42 eligible subjects and be conducted at 4 sites in the Netherlands. Clinical Trial Conditions: Bleeding During Liver Surgery Treatments in this Clinical Trial : Fibrocaps, Gelatin sponge Clinical Trial Phase: Phase 2 [...]
The desogestrel (150 mg) in combination with ethinyl estradiol (EE, 30 mg) is known as Marvelon in European countries. Previous studies revealed that the Marvelon is good and safe for women. As a study from Thailand showed that the Marvelon to be effective and acceptable in Thai women. Moreover compared to Caucasian women, the incidences [...]
The purpose of this study is to assess the long-term safety, tolerability and efficacy of LCZ696. Clinical Trial Conditions: Essential Hypertension Treatments in this Clinical Trial : LCZ696 Clinical Trial Phase: Phase 2 Eligible Clinical Trial Participant Age : Between 18 years to 100 years Can Healthy Volunteers Participate: No Clinical Trial Lead Sponsor: Novartis [...]
The investigators hypothesized that topical anti-inflammatory treatment could counteract the inflammatory reaction induced by EGFR'Is. Clinical Trial Conditions: Acneiform Rash Treatments in this Clinical Trial : Threolone ointment, ointment Synthomycine, Aqua cream lotion Clinical Trial Phase: Phase 2 Eligible Clinical Trial Participant Age : Between 18 years to 100 years Can Healthy Volunteers Participate: No [...]
Allogene MSCs transplantation will be performed in patients with chronic liver diseases through portal vein by ultrasound guiding and therapeutic effects including short-term effects and long-term follow-up will be compared and investigated. Clinical Trial Conditions: Allogene Transplantation, Chronic Liver Diseases Patients, Through Portal Vein by Ultrasound Guiding Eligible Clinical Trial Participant Age : Between 15 [...]
An effective and safe medical therapy would be most welcome to reduce the need for surgical interventions and related adverse events and psychological impact on patients with cervical cancer precursors. In this clinical trial, the investigators propose to evaluate the efficacy and safety of photodynamic therapy using hexaminolevulinate (HAL) for mild to moderate-grade CIN (grade [...]
Allogene MSCs transplantation will be performed in patients with chronic liver diseases through peripheral vein and therapeutic effects including short-term effects and long-term follow-up will be compared and investigated. Clinical Trial Conditions: Allogene MSCs Transplantation, Chronic Liver Diseases Patients, Peripheral Vein Eligible Clinical Trial Participant Age : Between 15 years to 65 years Can Healthy [...]
To determine whether Kristalose causes a significant increase in hydrogen and/or methane gas levels in patients requiring bowel evacuation, and also to determine the safety, efficacy, and patient preference of Kristalose as a bowel evacuant Clinical Trial Conditions: Bowel Evacuant Prior to Colonoscopy Treatments in this Clinical Trial : Kristalose Clinical Trial Phase: Phase 1 [...]
The primary objective of this study is to investigate the safety and tolerability of the anti-VEGFR-2 monoclonal antibody ramucirumab drug product in combination with docetaxel in Japanese patients with metastatic, or locally advanced breast cancer, with the aim of confirming the recommended dose of ramucirumab DP in combination with docetaxel. Clinical Trial Conditions: Locally Advanced [...]
To evaluate if a model of intervention based on a low-grade physical program prescribed in the dialysis centre and performed at home can modify the functional capacity and quality of life, reduce the risk of cardiovascular and all-causes mortality, non-fatal cardiovascular events and vascular access failure in dialysis patients. Clinical Trial Conditions: Patients on Dialysis [...]
The trial is a multi-centre, open-label, safety and tolerability extension trial to the IPH2101-101 (previously NN1975-1733) first human dose trial completed with a larger subject pool at an optimal dose level. The trial is conducted in elderly Acute Myeloid Leukemia (AML) patients over the age of 60 years, in complete remission, and who are not [...]
The purpose of this study is to evaluate sustained lung inflation followed by early nCPAP as delivery room ventilatory management for preterm neonates at risk of respiratory distress syndrome in reducing their need for mechanical ventilation and ameliorating lung injury without inducing adverse effects compared with intermittent bag and mask ventilation. Clinical Trial Conditions: Preterm [...]
The aim of this study is to determine, whether a liberal transfusion strategy is helpful to liberate patients from prolonged invasive mechanical ventilation. Patients who are difficult to wean according to the criteria by Boles et al [1] are limited by the capacity of their respiratory muscles. Improved oxygen delivery achieved by blood transfusions however [...]
The primary objective of this study is to evaluate the superior efficacy of quetiapine extended release(XR) mono-therapy, administered once daily compared to placebo, in the treatment of depressive symptoms in patients with Bipolar I and Bipolar II Disorder Clinical Trial Conditions: Bipolar Depression Treatments in this Clinical Trial : Quetiapine Fumarate (SEROQUEL) Extended Release, Placebo [...]
The hypothesis of this study is: Femoral nerve blocks can feasibly be performed on patients with Sickle Cell Disease and painful crisis in the Emergency Department. Clinical Trial Conditions: Sickle Cell Disease Treatments in this Clinical Trial : Femoral Nerve Block Clinical Trial Phase: Phase 1 Eligible Clinical Trial Participant Age : Between 18 years [...]
RATIONALE: Dasatinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving chemotherapy before a stem cell transplant stops the growth of cancer cells by stopping them from dividing or killing them. Monoclonal antibodies, such as alemtuzumab, can block cancer growth in different ways. Some block the [...]
This study aims to study prospectively for 8 months a sample of bipolar patients with acute depressive episode in order to identify that factors associated with functional impairment, with especial attention to the presence of subsyndromal symptoms beyond the acute phase. Clinical Trial Conditions: Bipolar Disorder, Bipolar Depression Eligible Clinical Trial Participant Age : Between [...]
The goal of this clinical research study is to learn if delayed-delayed breast reconstruction in women who require post-mastectomy radiation therapy will improve cosmetic outcomes and result in fewer complications compared to the standard approach (reconstruction that is not started until radiation treatment is completed). Clinical Trial Conditions: Breast Treatments in this Clinical Trial : [...]
