Prospective Study for 24-months of Physical Training Introduced in Lifestyle of Patients With FSHD : Tolerance Sustainability and Efficiency of Unsupervised Training Program.
It is now accepted that physical activity is not deleterious in myopathies, including
muscular dystrophies. In patients suffering from facioscapulohumeral dystrophy (FSHD),
aerobic training has been reported to be associated with physiological and functional
positive effects without alteration in quality of life. Van der Kooi et al. (2005) and Cup
et al. (2007) studies suggest that the combination of endurance and strength trainings is
even more relevant. However, only a few controlled and randomized studies have been
conducted on this topic and the impact of such training programs on skeletal muscle
regenerative capacities has not been addressed yet. Moreover, due to the fact that training
programs are mainly performed on short-term supervised periods, there is a lack of knowledge
regarding long-term effects, patient's autonomy and whether or not practice of regular
exercise can be maintained in patient's daily life. Also, only a few experiments report an
integrative view of potential benefits of such programs on functional, biological and
quality of life.
Clinical Trial Conditions: Muscular Dystrophy, Facioscapulohumeral
Treatments in this Clinical Trial : FSHD training
Eligible Clinical Trial Participant Age : Between 18 years to 100 years
Can Healthy Volunteers Participate: No
Clinical Trial Lead Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Detailed Clinical Trial Description: It is now accepted that physical activity is not deleterious in myopathies, including
muscular dystrophies. In patients suffering from facioscapulohumeral dystrophy (FSHD),
aerobic training has been reported to be associated with physiological and functional
positive effects without alteration in quality of life. Van der Kooi et al. (2005) and Cup
et al. (2007) studies suggest that the combination of endurance and strength trainings is
even more relevant. However, only a few controlled and randomized studies have been
conducted on this topic and the impact of such training programs on skeletal muscle
regenerative capacities has not been addressed yet. Moreover, due to the fact that training
programs are mainly performed on short-term supervised periods, there is a lack of knowledge
regarding long-term effects, patient's autonomy and whether or not practice of regular
exercise can be maintained in patient's daily life. Also, only a few experiments report an
integrative view of potential benefits of such programs on functional, biological and
quality of life.
The clinical trial information was obtained from http://clinicaltrials.gov/ct2/show/NCT01689480
