Genetic Predictors of Renal Dysfunction Following Heart Transplantation

Sep 17, 2012 No Comments by Casey

Kidney disease is a common problem after heart transplantation. It may be caused by
anti-rejection medications such as cyclosporine or tacrolimus. However, the reason why some
people develop kidney problems after a heart transplant, but other people do not, is not
fully known. This study plans to learn more about the relationship between a person's
genetic make-up (DNA) and the risk of kidney problems after a heart transplant. The
long-term goal of this research is to identify genetic variations that may help predict the
development of kidney problems after heart transplantation.

Clinical Trial Conditions: Heart Transplantation, Chronic Renal Insufficiency

Eligible Clinical Trial Participant Age : Between 18 years to 90 years

Can Healthy Volunteers Participate: No

Clinical Trial Lead Sponsor: University of Colorado, Denver

Detailed Clinical Trial Description: Kidney disease is a common problem after heart transplantation. It may be caused by
anti-rejection medications such as cyclosporine or tacrolimus. However, the reason why some
people develop kidney problems after a heart transplant, but other people do not, is not
fully known. This study plans to learn more about the relationship between a person's
genetic make-up (DNA) and the risk of kidney problems after a heart transplant. The
long-term goal of this research is to identify genetic variations that may help predict the
development of kidney problems after heart transplantation.

The clinical trial information was obtained from http://clinicaltrials.gov/ct2/show/NCT01686191

New Clinical Trial