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MostCare Versus Echo-Doppler for Cardiac Output Measurement

Sep 05, 2012 No Comments by

Recently, an uncalibrated minimally invasive PCM has been developed: the MostCare system.
This monitoring system is powered by Pressure Recording Analytical Method (PRAM), which is
based on the mathematical analysis of the arterial pressure profile changes. It allows
beat-to-beat SV assessment from the pressure signal recorded invasively in radial, brachial,
or femoral arteries. The most innovative features of this method are: 1) the lack of a
calibration requirement, 2) the analysis of the arterial wave signal is performed at 1000
Hz, 3) a dedicated arterial catheter-transducer is unnecessary. MostCare is powered by PRAM
(Pressure Recording Analytical Method) algorithm. The investigators primary end-point was to
evaluate the relationship between CO measured by MostCare with CO calculated with
Echo-Doppler in ICU patients under different clinical conditions. As a secondary end-point
the investigators evaluated the relationship between CO measured by MostCare with CO
obtained with thermodilution techniques (standard bolus thermodilution or transpulmonary
thermodilution, i.e. PiCCO system). This is a prospective multicentre observational study.

Clinical Trial Conditions: MostCare Versus Echo-Doppler for Cardiac Output Measurement

Eligible Clinical Trial Participant Age : Between 18 years to 100 years

Can Healthy Volunteers Participate: No

Clinical Trial Lead Sponsor: Azienda Ospedaliera Universitaria Senese

Detailed Clinical Trial Description: Recently, an uncalibrated minimally invasive PCM has been developed: the MostCare system.
This monitoring system is powered by Pressure Recording Analytical Method (PRAM), which is
based on the mathematical analysis of the arterial pressure profile changes. It allows
beat-to-beat SV assessment from the pressure signal recorded invasively in radial, brachial,
or femoral arteries. The most innovative features of this method are: 1) the lack of a
calibration requirement, 2) the analysis of the arterial wave signal is performed at 1000
Hz, 3) a dedicated arterial catheter-transducer is unnecessary. MostCare is powered by PRAM
(Pressure Recording Analytical Method) algorithm. The investigators primary end-point was to
evaluate the relationship between CO measured by MostCare with CO calculated with
Echo-Doppler in ICU patients under different clinical conditions. As a secondary end-point
the investigators evaluated the relationship between CO measured by MostCare with CO
obtained with thermodilution techniques (standard bolus thermodilution or transpulmonary
thermodilution, i.e. PiCCO system). This is a prospective multicentre observational study.

The clinical trial information was obtained from http://clinicaltrials.gov/ct2/show/NCT01678950

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By: ifood.tv