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Repetitive Transcranial Magnetic Stimulation and Intermittent Theta Burst (iTBS) in Schizophrenia

Mar 15, 2011 No Comments by

The pilot studies have showed that theta burst stimulation (TBS) can have the more rapid and
durable effects to the apply traditional rTMS protocols. The aim of this study is to
investigate the effect of repetitive TMS and theta burst in reduction of negative symptoms
and remission of cognitive functioning in patients with schizophrenia. In a randomized,
double blind clinical trials, 30 patients with schizophrenia in Razi psychiatric hospital
will be assigned to receive repetitive TMS; theta burst, or sham TMS, daily; for 20
sessions. The negative symptoms and cognitive functioning will be assessed before the
treatment (pre test) during the treatment (session 10), and after the treatment (post
test).QEEG and LORETA apply before and after rTMS in all subjects.

Clinical Trial Conditions: Schizophrenia

Treatments in this Clinical Trial : repetitive Transcranial Magnetic Stimulation (Magstim rapid2 ), repetitive Transcranial Magnetic Stimulation (Magstim rapid2), repetitive Transcranial Magnetic Stimulation(Magstim rapid2)

Clinical Trial Phase: Phase 2

Eligible Clinical Trial Participant Age : Between 18 years to 50 years

Can Healthy Volunteers Participate: No

Clinical Trial Lead Sponsor: University of Tehran

Detailed Clinical Trial Description: The pilot studies have showed that theta burst stimulation (TBS) can have the more rapid and
durable effects to the apply traditional rTMS protocols. The aim of this study is to
investigate the effect of repetitive TMS and theta burst in reduction of negative symptoms
and remission of cognitive functioning in patients with schizophrenia. In a randomized,
double blind clinical trials, 30 patients with schizophrenia in Razi psychiatric hospital
will be assigned to receive repetitive TMS; theta burst, or sham TMS, daily; for 20
sessions. The negative symptoms and cognitive functioning will be assessed before the
treatment (pre test) during the treatment (session 10), and after the treatment (post
test).QEEG and LORETA apply before and after rTMS in all subjects.

The clinical trial information was obtained from http://clinicaltrials.gov/ct2/show/NCT01315587

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By: ifood.tv