By: ifood.tv

Visual Sputum Suctioning System Tests in Mechanically Ventilated Patients

Apr 17, 2014 No Comments by

BACKGROUND: The investigators developed a fiber-optic-guided endotracheal suction catheter (visual sputum suctioning system or VSSS), which the investigators previously tested in vitro and animals. It integrates a 0.9-mm micro-imaging fiber into a 3.7-mm double-lumen catheter. PURPOSE: The purpose of this study was to investigate the safety and efficacy of sputum suctioning system in mechanical ventilated [...]

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Effect of Use of a New Technique for Pediatric Urine Collection in ER

Apr 17, 2014 No Comments by

Urinary tract infection is most common serious bacterial infection in children who admit into the emergency department (ED). However the collection of urine from young children is time consuming process. So many children and their family guardian waste time until medical disposition established. In 2013, Maria Luisa Herreros Fernandez etc have suggested a new urine [...]

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Safety and Efficacy Study of Fibrocaps to Treat Surgical Bleeding in Children

Apr 17, 2014 No Comments by

The purpose of the study is to show that Fibrocaps plus gelatin sponge is better than gelatin sponge alone in stopping mild to moderate bleeding in children having surgery Clinical Trial Conditions: Surgical Bleeding Treatments in this Clinical Trial : Fibrocaps plus gelatin sponge, Gelatin Sponge Clinical Trial Phase: Phase 2 Eligible Clinical Trial Participant [...]

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Galectin Inhibitor (GR-MD-02) and Ipilimumab in Patients With Metastatic Melanoma

Apr 17, 2014 No Comments

The goal of this study is to determine a safe dose of GR-MD-02 used in combination with the FDA-approved dose of ipilimumab (3 mg/kg) in patients who have advanced melanoma. GR-MD-02 is a galectin. Galectins are a family of proteins that have numerous functions in normal mammalian biology including the facilitation of cell-cell interactions, regulation [...]

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Phase 1 Study to Evaluate MEDI4736

Apr 17, 2014 No Comments

This is a multicenter, open-label, Phase 1 study to assess the safety and antitumor activity of MEDI4736 in subjects with myelodysplastic syndrome. Clinical Trial Conditions: Myelodysplastic Syndrome Treatments in this Clinical Trial : MEDI4736 Clinical Trial Phase: Phase 1 Eligible Clinical Trial Participant Age : Between 18 years to 100 years Can Healthy Volunteers Participate: [...]

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An Open-Label Single-Dose Study to Determine the Metabolism and Elimination of 14C-Perampanel in Healthy Male Subjects

Apr 17, 2014 No Comments

This is an open-label, single-dose study in healthy male subjects. The study will have 2 phases: Pretreatment and Treatment. The Pretreatment Phase will last up to 21 days and will consist of a Screening Period and a Baseline Period, during which each subject's study eligibility will be determined and baseline assessments will be conducted. Clinical [...]

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Evaluation of Renal Function Efficacy and Safety When Switching From Tenofovir/Emtricitabine Plus a Protease Inhibitor/Ritonavir to a Combination of Raltegravir (MK-0518) Plus Nevirapine Plus Lamivudine in HIV-1 Participants With Suppressed Viremi…

Apr 17, 2014 No Comments

To evaluate changes in renal function, efficacy, and safety when switching from a combination of tenofovir/emtricitabine (TDF/FTC) plus a protease inhibitor/ritonavir (PI/r) to a combination of raltegravir (MK-0518) plus nevirapine plus lamivudine in human immunodeficiency virus (HIV)-1 participants with suppressed viremia and impaired renal function (MK-0518-284) Clinical Trial Conditions: HIV Infections Treatments in this Clinical [...]

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Go Girls! Fitness Support Group Intervention Effectiveness Study

Apr 17, 2014 No Comments

The main purpose of this study is to determine if the Go Girls! program to take place at the Kluge Children's Rehabilitation Center Therapeutic Recreation Gymnasium, intended to introduce girls to a fun, non-threatening environment of exercise with peer support, improves scores on a physical activity enjoyment scale (PACES). Information regarding enjoyment of physical activity [...]

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Analysis of Patients Treated for Chronic Granulomatous Disease Since January 1 1995

Apr 17, 2014 No Comments

This study is a longitudinal and cross-sectional evaluation of patients with Chronic Granulomatous Disease (CGD) who received or are receiving hematopoietic cell transplantation (HCT) for their disease under a variety of protocols used by participating institutions compared to a control non-HCT group receiving standard care. Investigators at multiple centers caring for patients with CGD in [...]

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A Phase 2 Study of Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung Cancer

Apr 17, 2014 No Comments

This study will test whether vaccination with Viagenpumatucel-L combined low-dose cyclophosphamide followed by sequential chemotherapy will prolong the survival of patients with non-small cell lung cancer (NSCLC) who have failed two prior lines of therapy compared with chemotherapy alone. Patients will be randomized 2 to 1 into the Viagenpumatucel-L arm and the chemotherapy alone arm, [...]

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A Phase 1 Study of Daratumumab in Japanese Participants With Relapsed or Refractory Multiple Myeloma

Apr 17, 2014 No Comments

The purpose of this study is to evaluate the tolerability and safety of Daratumumab in Japanese participants with relapsed (the return of a medical problem) or refractory (not responding to treatment) multiple myeloma (cancer of plasma cells in bone marrow, characterized by the presence of abnormal proteins in the blood). Clinical Trial Conditions: Multiple Myeloma [...]

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Zinc Gel and Epidermal Regeneration in Healthy Human Volunteers

Apr 17, 2014 No Comments

Zinc is an important metal for the maintenance of healthy skin and wound healing. Washing with detergents e.g. shower gels may deplete the zinc stores in the skin. The purpose of our study is to see whether repeated washing with zinc containing shower gel of superficial wounds will result in increased healing. Clinical Trial Conditions: [...]

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Absorption Profiles of Three Polyphenol Preparations With and Without Pollen Shell Covering

Apr 17, 2014 No Comments

This study consists of two parts. The first part of the study will look at the absorption of three different polyphenol preparations into the blood, the variability of their absorption and whether their absorption can be enhanced by mixing with pollen shells (pollen shells have been shown to enhance lipid molecule absorption). For this purpose [...]

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Influence of Cognitive Rest on Minor Traumatic Brain Injury

Apr 17, 2014 No Comments

Background: Head injury is a common presentation to family medicine clinics and emergency departments (EDs), and the majority will not result in intracranial injury requiring neurosurgical consultation, but will have symptoms of mild traumatic brain injury (MTBI). It is estimated between 15-50% of patients with MTBI develop post-concussive syndrome (PCS). Research in the management of [...]

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Blinded Randomized Study of Gabapentin (Neurontin ) and Gabapentin Enacarbil (Horizant ) in Restless Leg Syndrome

Apr 17, 2014 No Comments

The study will compare the safety, effectiveness and tolerability of gabapentin (Neurontin) versus gabapentin enacarbil (Horizant) as treatment restless leg syndrome. Clinical Trial Conditions: Restless Leg Syndrome Treatments in this Clinical Trial : Gabapentin immediate release (Neurontin), Gabapentin enacarbil extended release (Horizant) Clinical Trial Phase: Phase 4 Eligible Clinical Trial Participant Age : Between 18 [...]

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BMN-673 and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies

Apr 17, 2014 No Comments

This phase I/II trial studies the side effects and best dose of BMN-673 and temozolomide and to see how well they work in treating younger patients with tumors that have come back or have not responded to standard therapy. BMN-673 may stop the growth of cancer cells by blocking some of the enzymes needed for [...]

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A Study to Evaluate Enzalutamide After Abiraterone in Metastatic Castration-Resistant Prostate Cancer

Apr 17, 2014 No Comments

The objective of this study is to evaluate the efficacy and safety of enzalutamide treatment in patients with progressive metastatic castration-resistant prostate cancer previously treated with abiraterone acetate. Clinical Trial Conditions: Metastatic Castration-resistant Prostate Cancer Treatments in this Clinical Trial : enzalutamide Clinical Trial Phase: Phase 4 Eligible Clinical Trial Participant Age : Between 18 [...]

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Rubidium Elution System Performance Testing

Apr 17, 2014 No Comments

Rubidium is a newly approved nuclear medicine imaging drug or 'tracer' used to look at blood flow in the heart. This tracer is given using a special pump called an 'elution system' which is considered investigational. This means the device is not yet approved by Health Canada for general use, but it has been approved [...]

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Dual-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy (DLTCI)

Apr 17, 2014 No Comments

Laparoscopic Cholecystectomy applied to Artificial pneumoperitoneum and the extent of Surgical stimulation cause the wave of hemodynamics increase vigorously, which make it difficult to judge the depth of anesthesia according to traditional hemodynamics index such as heart rate and blood pressure.In case of this, the investigators design this research to study the Closed-Loop Target Controlled [...]

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Treatment of Tracheostomy Granulomas

Apr 17, 2014 No Comments

This study plans to learn more about the different ways used to treat tracheostomy granulomas. Investigators want to see which standard of care method (steroid application, silver nitrate, or betadine) is more successful in treating tracheostomy granulomas. Clinical Trial Conditions: Granuloma, Tracheostomy Treatments in this Clinical Trial : Betadine, Silver Nitrate, Hydrocortisone Butyrate Cream, 0.1% [...]

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Antiemetic Therapy With or Without Olanzapine in Preventing Chemotherapy-Induced Nausea and Vomiting in Patients With Cancer Receiving Highly Emetogenic Chemotherapy

Apr 17, 2014 No Comments

This randomized phase III trial studies antiemetic (prevents or reduces nausea and vomiting) therapy with olanzapine to see how well they work compared to antiemetic therapy alone in preventing chemotherapy-induced nausea and vomiting in patients with cancer receiving highly emetogenic (causes vomiting) chemotherapy. Antiemetic drugs, such as palonosetron hydrochloride, ondansetron, and granisetron hydrochloride, may help [...]

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Effects of Rifaximin in Patients With Acute Alcoholic Hepatitis

Apr 17, 2014 No Comments

Acute alcoholic hepatitis (AAH) is a serious condition and one of the most frequent causes of Acute-on-Chronic Liver Failure. The current standard therapy (corticosteroids) is theme of debate and unsatisfactory in many patients (year mortality: 30%). One of the main causes of death is bacterial infections, which affect 40-50% of patients at 90 days. Intestinal [...]

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The Tolerability of Saracatinib in Subjects With Lymphangioleiomyomatosis (LAM) (SLAM-1)

Apr 17, 2014 No Comments

Lymphangioleiomyomatosis (LAM) is a rare lung disease that mostly affects women of childbearing age. In LAM, abnormal, muscle-like cells begin to grow out of control in the lungs. As a result, air can't move freely in and out of the lungs. In some cases, this means the lungs can't supply the body's other organs with [...]

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An Open Label Multi-center Extension Study to Evaluate Long-term Safety/ Tolerability of Dovitinib in Patients With Solid Tumors Who Continue to Receive Treatment With Dovitinib (TKI258) in Novartis-sponsored Single Agent Dovitinib Studies Which Fulf…

Apr 17, 2014 No Comments

The study allows continued safety follow-up of single agent dovitinib in patients who are on single agent dovitinib treatment in a Novartis-sponsored study which has met its primary endpoint and are benefiting from the treatment as judged by the investigator. Clinical Trial Conditions: Solid Tumors Treatments in this Clinical Trial : Dovitinib Eligible Clinical Trial [...]

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Urine pH and Diet Net Acid Load

Apr 17, 2014 No Comments

Presently, the gold standard for testing diet acid intake is a urine collection done for many hours, usually 24 hours, which must be analyzed in a research lab for "net acid excretion". So, getting information about diet acid intake is difficult. Many people have suggested doing a much simpler test, which is checking the pH [...]

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By: ifood.tv