By: ifood.tv

A Study of LY3079514 in Healthy Participants

Sep 18, 2014 No Comments by

The main purpose of this study is to evaluate the safety and how well the body will handle a single dose of study drug, LY3079514. This study will last about 12 weeks for each participant. Clinical Trial Conditions: Healthy Volunteers Treatments in this Clinical Trial : LY3079514, LY3079514, Placebo, Placebo Clinical Trial Phase: Phase 1 [...]

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Safety and Effectiveness of Different ShangRing Device Sizes for Adult Male Circumcision in Lusaka Zambia

Sep 18, 2014 No Comments by

The purpose of this study is to assess the safety of ShangRing MMC procedures when providers choose among 7 adult sizes (reduced-sizes or treatment arm) versus the full range of 14 adult sizes (all-sizes or control arm) during routine service delivery in Lusaka, Zambia. Clinical Trial Conditions: HIV Prevention Treatments in this Clinical Trial : [...]

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Surgical Excision Versus Curettage Prior to Imiquimod for the Treatment of Nodular Basal Cell Carcinoma

Sep 18, 2014 No Comments by

Basal cell carcinoma (BCC) is a slow-growing, locally invasive malignant epidermal skin tumour. It is the most common malignant disease in Caucasians, representing approximately 80% of all cases of skin cancer and is therefore an important health problem. In the Netherlands incidence rates are 165 for men and 157 for women per 100.000 person-years, and [...]

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A Phase 1 Study Evaluating CB-5083 in Patients With Advanced Solid Tumors

Sep 18, 2014 No Comments

This is a multicenter, open-label, phase 1 study of orally administered CB-5083 in adult patients with advanced solid tumors who have progressed or are non-responsive to available therapies and for which no standard therapy exists. The study will be conducted in 2 parts: an initial Dose Escalation Phase (phase 1a) of CB-5083 in patients with [...]

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Pathophysiological Study of the Increase in Pancreatic Volume in Type 2 Diabetes Treatments.

Sep 18, 2014 No Comments

Incretinomimetics and inhibitors of dipeptidyl peptidase-4 (DPP-4) are new treatments for diabetes. Previous retrospective studies have shown that these treatments induced an increase in pancreatic mass with potentially a risk for pancreatitis and development of precancerous lesions. The aim of our study is to provide a better understanding of the pathophysiological mechanisms of increased volume [...]

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Pilot #2 of Social Network Intrauterine Contraceptive (IUC) Intervention

Sep 18, 2014 No Comments

This study has two goals: 1) to test an approach to helping women who use intrauterine contraception (IUC) spread the word about this type of long-lasting, highly effective birth control method among their friends and family and; 2) to test ways of getting in touch with these women's friends and family so that we can [...]

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Establish Quantitative Measurements of Laryngeal Sensorimotor Functions and Evaluating the Grade of Phonation and Swallowing Impairment

Sep 18, 2014 No Comments

Laryngeal motor and sensory nerve dysfunction may cause phonation and swallowing disturbance, which often happens after the treatment for laryngopharyngeal and esophageal cancer and may induce fatal complications such as aspiration pneumonia. By the conventional examinations, the tiny sensory or motor changes are hard to be detected before complete vocal paralysis. It is utmost important [...]

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Mail Outreach To Increase Vaccination Acceptance Through Engagement

Sep 18, 2014 No Comments

The aim of this study is to determine whether receiving a core letter signed by the Surgeon General or the Director of the National Vaccine Program that provides only information about influenza, or a core letter signed by the Surgeon General with an added basic or enhanced implementation prompt, will increase rates of influenza vaccination [...]

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AF Ablation With or Without ROX Coupler Study

Sep 18, 2014 No Comments

The study will test the hypothesis that ablation of paroxysmal atrial fibrillation in hypertensive subjects is more effective when a ROX coupler is inserted concurrently. Clinical Trial Conditions: Atrial Fibrillation, Hypertension Treatments in this Clinical Trial : Atrial fibrillation ablation, ROX Coupler insertion Clinical Trial Phase: Phase 4 Eligible Clinical Trial Participant Age : Between [...]

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Study of the Efficacy and Safety of Cholecalciferol Supplementation on the Activity of Rheumatoid Arthritis in Patients With Vitamin D Deficiency

Sep 18, 2014 No Comments

Vitamin D plays a key role in the regulation of calcium metabolism and bone physiology and also presents immunomodulatory effects. In contrast to healthy individuals, macrophages and synoviocytes synovium of patients with rheumatoid arthritis (RA) have receptors for vitamin D. In vitro, 1,25 Vitamin D inhibits T cell proliferation and cytokine synthesis and decreases pro-inflammatory [...]

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24-Week Multicenter Randomized Parallel-group Open-label Active Controlled Phase IV Study to Assess the Efficacy Safety and Tolerability of Saxagliptin Compared With Acarbose When in Combination With Metformin in Patients With T2D Inadequately …

Sep 18, 2014 No Comments

SMART Study – A 24-Week, Multicenter, Randomized, Parallel-group, Open-label, Active Controlled Phase IV Study to Assess the Efficacy, Safety and Tolerability of Saxagliptin Compared with Acarbose when in Combination with Metformin in Patients with Type 2 Diabetes Mellitus (T2D) Inadequately Controlled with Metformin Monotherapy Clinical Trial Conditions: Type 2 Diabetes Mellitus Treatments in this Clinical [...]

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Study to Examine the Cytokine Levels Gene Expression and Safety of a Single Nasal Dose of JNJ-43260295 in Healthy Participants and Atopic Participants With Mild to Mild-Persistent Asthma

Sep 18, 2014 No Comments

The purpose of this study is to investigate the cytokine levels in nasal lavage and gene expression in nasal scraping following a single nasal dose of JNJ-43260295 in healthy participants, and in atopic mild to mild-persistent asthmatic (breathing disorder in which there is wheezing and difficulty in breathing) participants with and without nasal allergen challenge [...]

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Effects of Growth Hormone (GH) Deficiency and Growth Hormone Replacement on Serum Fibroblast Growth Factor 21 (FGF21)

Sep 18, 2014 No Comments

This study will recruit healthy controls (who have normal GH production and growth hormone levels) and patients identified as having GHD, who are deemed eligible for GH replacement therapy according to NICE guidelines. The patients recruited will have been identified as starting on GH by their referring clinicians and a decision made on their replacement [...]

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Respiratory Muscles and Inspiratory Muscle Training

Sep 18, 2014 No Comments

The effects of inspiratory muscle training (IMT) remain controversial. Many studies have examined the effect IMT has on exercise performance, but any changes to the body that come from IMT have yet to be looked at. This study will look at how someone breathes can change after IMT. Understanding how IMT changes the body can [...]

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Lambrolizumab in Treating Patients With Relapsed or Refractory Stage IIB-IVB Mycosis Fungoides or Sezary Syndrome

Sep 18, 2014 No Comments

This phase II trial studies how well lambrolizumab works and the side effects it causes in patients with stage IIB-IVB mycosis fungoides or Sezary syndrome that has not responded to at least one type of treatment. Lambrolizumab may stimulate the immune system to destroy cancer cells by increasing production of a type of cell that [...]

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A Study of How the Body Breaks Down and Eliminates LY2623091

Sep 18, 2014 No Comments

This type of study is called a radiolabeled study. For this study, LY2623091 (study drug) has been specially prepared to contain radiolabeled carbon [^14C]. [^14C] is a naturally occurring radioactive form of the element, carbon. This study will increase understanding about how the drug appears in the blood, urine, and stool after it is administered [...]

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Impact of 50% Nitrous Oxide Inhalation on Pain and Anxiety Induced by Lumbar Puncture: a Double-blind Randomized Controlled Trial

Sep 18, 2014 No Comments

This study is designed to evaluate the analgesic effect of nitrous oxide (N2O) on the pain induced during lumbar puncture. Clinical Trial Conditions: Lumbar Puncture Treatments in this Clinical Trial : 50:50 mixture of nitrous oxide/oxygen Clinical Trial Phase: Phase 4 Eligible Clinical Trial Participant Age : Between 18 years to 60 years Can Healthy [...]

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Cabozantinib-s-malate in Treating Patients With Relapsed Osteosarcoma or Ewing Sarcoma

Sep 18, 2014 No Comments

This phase II trial studies how well cabozantinib-s-malate works in treating patients with osteosarcoma or Ewing sarcoma that has grown or returned. Cabozantinib-s-malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Clinical Trial Conditions: Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Metastatic Osteosarcoma, Recurrent Ewing Sarcoma/Peripheral Primitive [...]

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Molecular Profiling in Tissue Samples From Patients With Cancer Who Are Exceptional Responders to Treatment

Sep 18, 2014 No Comments

This pilot research trial studies molecular profiling in tissue samples from patients with cancer who got better with treatment that didn't work for most other patients with the same disease. Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and [...]

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Effect of Yoga on Life Quality and Immunity in Breast Cancer Patients After Operation and or Chemotherapy

Sep 18, 2014 No Comments

The purpose of study is to investigate if yoga exercise improve life quality and immune status in breast cancer patients after complete treatment (including surgery and / or radiotherapy and / or chemotherapy) Clinical Trial Conditions: Female Breast Carcinoma Treatments in this Clinical Trial : Yoga exercise Eligible Clinical Trial Participant Age : Between 20 [...]

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A Phase 1 Study of Oprozomib to Assess Food Effect Drug-Drug Interaction With Midazolam and Safety and Tolerability in Patients With Advanced Malignancies

Sep 18, 2014 No Comments

The purpose of this Phase 1 of the study is to evaluate the effect of food on the pharmacokinetics (PK) of oprozomib, the drug-drug interaction of oprozomib with midazolam, and the safety and tolerability of oprozomib in patients with advanced malignancies. Clinical Trial Conditions: Advanced Non-Central Nervous System (CNS) Malignancies Treatments in this Clinical Trial [...]

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Screening of Volunteers for Clinical Trials of Investigational or Licensed Vaccines or Antiviral Products

Sep 18, 2014 No Comments

Vaccines and antiviral therapies are critical for prevention and treatment of viral diseases. Among other things, testing of vaccines or antiviral medications requires knowing whether the prospective subject has been previously infected by the virus to be studied. We will recruit healthy persons for this study and screen them for their eligibility to potentially participate [...]

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Effects of Psilocybin-facilitated Experience on the Psychology and Effectiveness of Professional Leaders in Religion

Sep 18, 2014 No Comments

The current protocol is a pilot study of the effects and possible utility of psilocybin-facilitated experiences for professional religious leaders. Clinical Trial Conditions: Healthy Treatments in this Clinical Trial : Psilocybin Clinical Trial Phase: Phase 1 Eligible Clinical Trial Participant Age : Between 25 years to 80 years Can Healthy Volunteers Participate: Yes Clinical Trial [...]

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Effect of Probenecid on Synovial Fluid ATP Levels in CPPD

Sep 18, 2014 No Comments

This study will investigate the hypothesis that probenecid, a medication currently used for gout, reduces levels of ATP in the joint fluid of patients with calcium pyrophosphate deposition disease (CPPD), another common type of crystal-related arthritis. There is good evidence that CPPD results from an excess of ATP in joints. We will measure levels of [...]

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Effects of Co-administration of Canagliflozin 300 mg and Phentermine 15 mg With Placebo in the Treatment of Non-Diabetic Overweight and Obese Participants

Sep 18, 2014 No Comments

The purpose of this study is to compare the effects of canagliflozin and phentermine to those of placebo to promote on a change in body weight over a 26 week period. Clinical Trial Conditions: Obesity Treatments in this Clinical Trial : Canagliflozin, Phentermine, Matching Placebo to Canagliflozin, Matching Placebo to Phentermine Clinical Trial Phase: Phase [...]

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By: ifood.tv