By: ifood.tv

Ublituximab in Combination With Ibrutinib Versus Ibrutinib Alone in Patients With Previously Treated High-Risk Chronic Lymphocytic Leukemia (CLL)

Nov 25, 2014 No Comments by

This study evaluates the addition of ublituximab, a novel monoclonal antibody, to ibrutinib compared to ibrutinib alone in previously treated Chronic Lymphocytic Leukemia (CLL) patients with high-risk cytogenetic features. Half of the participants will receive ublituximab in combination with ibrutinib, while the other half will receive ibrutinib alone. Clinical Trial Conditions: Chronic Lymphocytic Leukemia Treatments [...]

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Pretargeted Radioimmunotherapy in Metastatic Colorectal Cancer

Nov 25, 2014 No Comments by

Phase I/II, Open-labeled, Prospective, Multi-center study of a Pretargeted Radioimmunotherapy in metastatic colorectal cancer with ractionated injections of TF2 plus 90Y-IMP288 (RITCOLON). Clinical Trial Conditions: Metastatic Colorectal Cancer Treatments in this Clinical Trial : Antibody TF2, 90-Y-IMP-288, 111-In-IMP-288 Eligible Clinical Trial Participant Age : Between 18 years to 100 years Can Healthy Volunteers Participate: No [...]

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Efficacy of Continuous Glucose Monitoring in Neonates With Hypoglycemia

Nov 25, 2014 No Comments by

Our aim is to determine the feasibility of using continuous glucose monitors (CGMs) in infants with low blood glucose to improve how we care for these infants. To do this we plan on monitoring blood glucose levels with CGMs (instead of only with intermittent bloodsampling) in late-preterm and term infants admitted to the NICU who [...]

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Evaluation of Allium Ampeloprasum Spp.Iranicum Cream Effect for the Management of Hemorrhoids Symptoms

Nov 25, 2014 No Comments

Purpose of study is evaluation of Allium ampeloprasum Spp.Iranicum cream efficacy in management of symptomatic hemorrhoids in a double blind randomized placebo-control trial Clinical Trial Conditions: Hemorrhoids Treatments in this Clinical Trial : Allium Ampeloprasum Spp.Iranicum Cream, placebo topical cream, Anti hemorrhoid topical cream Eligible Clinical Trial Participant Age : Between 18 years to 65 [...]

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Pazopanib as Front-Line Therapy in Patients With Non-Resectable or Metastatic Soft Tissue Sarcomas Who Are Not Candidates for Chemotherapy

Nov 25, 2014 No Comments

Pazopanib is FDA approved as a second line and beyond treatment for metastatic soft tissue sarcoma. There is a population of elderly and debilitated soft tissue sarcoma patients that are not fit for standard first line chemotherapy that is doxorubicin based. As pazopanib is well tolerated with minimal side effects, the investigators propose a phase [...]

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Fluoroscopically-guided Epidural Block in the Midthoracic Region: A Comparison of Anterioposterior Versus Oblique View Approach

Nov 25, 2014 No Comments

A comparison of anterioposterior versus oblique view approach method for fluoroscopically-guided epidural block in the midthoracic region. The investigators evaluate differences on total radiation time and technical feasibility between anterioposterior and oblique view approach method. Clinical Trial Conditions: Low Back Pain Requiring Epidural Injection Treatments in this Clinical Trial : oblique view approach Eligible Clinical [...]

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Pharmacokinetic Analysis of Nicotinamide Riboside

Nov 25, 2014 No Comments

Nicotinamide riboside is a newly discovered vitamin B3. The pharmacokinetics in humans is so far not analyzed. Clinical Trial Conditions: Healthy Participants Treatments in this Clinical Trial : Nicotinamide riboside Eligible Clinical Trial Participant Age : Between 18 years to 30 years Can Healthy Volunteers Participate: Yes Clinical Trial Lead Sponsor: Aarhus University Hospital Detailed [...]

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Transesophageal Echocardiographic Evaluation of the Effect of Dexmedetomidine Infusion as an Adjuvant to General Anesthesia on the Cardiac Function

Nov 25, 2014 No Comments

Dexmedetomidine is a selective alpha-2 adrenergic agonist that can be considered as an adjuvant to propofol or inhalational anesthetics. Dexmedetomidine mediate its cardiovascular effect through activation of receptors in central and peripheral nervous system. The classic cardiovascular response of dexmedetomidine is the biphasic with initial short-term increase in blood pressure followed by long-lasting decrease in [...]

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Clinical Study of POSS-PCU Vascular Grafts for Vascular Access

Nov 25, 2014 No Comments

This study evaluates the safety and performance of a new vascular graft made of POSS-PCU as a vascular access conduit for haemodialysis. 30 patients requiring access for dialysis will be enrolled and monitored at regular intervals for 18 months. Clinical Trial Conditions: Renal Insufficiency Treatments in this Clinical Trial : POSS-PCU vascular graft Eligible Clinical [...]

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Investigation on Safety Tolerability and Pharmacokinetics of Single Doses of NNC0174-0833 in Overweight to Obese But Otherwise Healthy Male Subjects

Nov 25, 2014 No Comments

This trial is conducted in the United States of America (USA). The aim of the trial is to investigate the Safety, Tolerability and Pharmacokinetics of Single Doses of NNC0174-0833 in Overweight to Obese but Otherwise Healthy Male Subjects. Clinical Trial Conditions: Obesity, Healthy Treatments in this Clinical Trial : NNC0174-0833, placebo Clinical Trial Phase: Phase [...]

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Enzalutamide in Combination With Gemcitabine and Cisplatin in Bladder Cancer

Nov 25, 2014 No Comments

The main purpose of this study is to find out the dose of enzalutamide that can be safely given with gemcitabine and cisplatin in patients with advanced bladder cancer. Researchers also want to find out the side effects of these drugs when given together. This study will also help in finding out the effect on [...]

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Role of Anti-IgE in Severe Childhood Eczema

Nov 25, 2014 No Comments

To evaluate the efficacy of anti-IgE (Omalizumab/Xolair) in children with severe eczema. Clinical Trial Conditions: Atopic Eczema, Atopic Dermatitis, Child Treatments in this Clinical Trial : Xolair, Placebo Clinical Trial Phase: Phase 4 Eligible Clinical Trial Participant Age : Between 4 years to 19 years Can Healthy Volunteers Participate: No Clinical Trial Lead Sponsor: Guy's [...]

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Community Engagement for Early Recognition and Immediate Action in Stroke

Nov 25, 2014 No Comments

We plan to develop and adapt a community-partnered intervention using community health promoters ("Stroke Promoters") to deliver messaging regarding stroke symptom awareness and the need for calling 911 after stroke onset. We will implement this intervention in 2 large south side Chicago communities and measure the impact on symptom onset to hospital arrival times and [...]

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Impact of Urethral Mobility on the Success of Sling Operations

Nov 25, 2014 No Comments

Main objective is to evaluate the relation between the increased urethral mobility and unsuccessful treatment after TVT and TOT operations. 140 patients will be included in the research who are planned to have TVT and TOT operations with SUI and MUI diagnoses.Female patients of 25 to 70 years of age who are positive for stress [...]

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Study of Safety Efficacy of Fulranumab Adjunctive Use in OA of Hip or Knee PAI3007

Nov 25, 2014 No Comments

The purpose of this study is to demonstrate the efficacy, safety, and tolerability of fulranumab as adjunctive therapy compared with placebo in participants with signs and symptoms of osteoarthritis of the hip or knee that are not adequately controlled by current pain therapy. Clinical Trial Conditions: Osteoarthritis, Pain Treatments in this Clinical Trial : Placebo, [...]

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Diet for Colonoscopy Preparation in Diabetic Patients

Nov 25, 2014 No Comments

This trial will compare the efficacy of to 2 different sets of dietary recommendations to be followed before colon cleansing for colonoscopy in diabetic patients. Clinical Trial Conditions: Diabetes Mellitus, Colonic Diseases Treatments in this Clinical Trial : Low-residue diet, Usual care Clinical Trial Phase: Phase 3 Eligible Clinical Trial Participant Age : Between 18 [...]

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Qsymia as an Adjunct to Surgical Therapy in the Superobese

Nov 25, 2014 No Comments

This study tests the efficacy of the medication, Qsymia, as an adjunct therapy in superobese individuals planning to undergo weight loss surgery. Individuals taking the medication before and after surgery will be compared to historical controls who had surgery without taking the medication. Clinical Trial Conditions: Obesity, Metabolic Surgery, Weight Loss, Bariatric Surgery Procedures Treatments [...]

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Buparlisib (BKM120) In Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Recurrent/Refractory Secondary Central Nervous System Lymphoma (SCNSL)

Nov 25, 2014 No Comments

The purpose of this study is to find out what effects, good and/or bad, Buparlisib (also known as BKM120) has on lymphoma and the central nervous system. Clinical Trial Conditions: Lymphoma, Primary Central Nervous System Lymphoma, Recurrent/Refractory Secondary Central Nervous System Lymphoma Treatments in this Clinical Trial : Buparlisib (BKM120) Clinical Trial Phase: Phase 2 [...]

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Post-Marketing Surveillance of Long-Term Observation of Gliadel Wafer-Investigation of Vital Prognosis in Patients With High Grade Glioma

Nov 25, 2014 No Comments

The objective of this study is to determine the survival status of patients enrolled in study GLI01S (all-case observational study). Clinical Trial Conditions: Malignant Glioma Treatments in this Clinical Trial : No intervention Eligible Clinical Trial Participant Age : Between 0 years to 100 years Can Healthy Volunteers Participate: No Clinical Trial Lead Sponsor: Eisai [...]

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Distance Savvy: Testing Tele-Savvy a Distance Dementia Family Caregiver Education Program

Nov 25, 2014 No Comments

The purpose of this study is to refine and test the web-based delivery of a well-established in-person group program that provides information and education to informal caregivers (family and friends) of persons with Alzheimer's disease (or related illnesses). Clinical Trial Conditions: Dementia, Alzheimer's Disease, Depression Treatments in this Clinical Trial : Tele-Savvy, Tele-Savvy, iPad Eligible [...]

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Observational Study of the Combination of Post-transplant High Dose Cyclophosphamide Tacrolimus and Mycophenolate Mofetil for the Prevention of Acute Graft-versus-Host Disease in Patients Eligible to Allogeneic Hematopoietic Stem Cell Transplant

Nov 25, 2014 No Comments

This observational study is proposed to observe the effect of high-dose, post-transplantation cyclophosphamide after a T cell-replete, HLA-matched PBSC graft from an HLA-identical or mismatched donor. Clinical Trial Conditions: Hematological Malignancies Eligible Clinical Trial Participant Age : Between 18 years to 65 years Can Healthy Volunteers Participate: No Clinical Trial Lead Sponsor: Fondazione del Piemonte [...]

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A Comparative Effectiveness RCT of Optimized Cessation Treatments

Nov 25, 2014 No Comments

This study is a 2-arm randomized clinical trial (RCT). Participants motivated to quit smoking will be randomized to one of two treatments: 1) a Modern Usual Care (M-UC) vs. 2) Abstinence-Optimized Cessation Treatment (AOCT). The components for the optimized treatment have strong theoretical and empirical support from the investigators previous screening studies. Clinical Trial Conditions: [...]

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Project 1 Study 2: The Combined Impact of Nicotine Replacement and Spectrum Cigarettes

Nov 25, 2014 No Comments

Project 1, Study 2 will evaluate the impact of very low nicotine content cigarettes with and without transdermal nicotine on cigarettes smoked per day, nicotine exposure, discomfort/dysfunction, other health-related behaviors, nicotine/tobacco dependence, biomarkers of tobacco exposure, intention to quit, compensatory smoking, other tobacco use, cigarette characteristics, cue reactivity, cardiovascular function, perceived risk and cue reactivity. [...]

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Effect of GS-6615 on Shortening of the QT Interval Safety and Tolerability in Adults With Long QT-3 Syndrome

Nov 25, 2014 No Comments

This study will evaluate the effect of GS-6615 on shortening of the corrected QT interval (QTc), safety, and tolerability in adults with type 3 long QT syndrome (LQT3). During the single-blind treatment period (24 weeks), participants will receive GS-6615 and/or placebo to match GS-6615. Following the single-blind treatment period, participants who have not permanently discontinued [...]

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Feasibility Neurocognitive Outcome After Transplant

Nov 25, 2014 No Comments

This pilot study will primarily be evaluated by feasibility and adherence to an iPad-based neurocognitive intervention program. It will secondarily be evaluated by performance on the neurocognitive testing post-transplant and change in performance in subsequent years. Clinical Trial Conditions: Stem Cell Transplantation, Pediatric Cancer, Acute Lymphoblastic Leukemia Treatments in this Clinical Trial : Cognitive rehabilitation [...]

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By: ifood.tv