By: ifood.tv

Evaluation of Oral Care to Prevent Oral Mucositis in ER Positive MBC Patients Treated With Everolimus: Phase 3 RCT

Mar 03, 2015 No Comments by

To examine whether the occurrence of oral mucositis can be reduced by dental oral management in patients by comparing the use of dental oral management through instruction by dental and oral surgeons (dental oral management group) and an observation group (brushing instruction only group) in a randomized, controlled study in females that are using everolimus [...]

New Clinical Trial Read more

A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor

Mar 03, 2015 No Comments by

The study's primary objective is to demonstrate the superiority of retosiban to prolong pregnancy and improve neonatal outcomes compared with placebo. It is a Phase III, randomized, double-blind, parallel-group, multicenter study and will be conducted in approximately 900 females, aged 12 to 45 years, with an uncomplicated, singleton pregnancy and intact membranes in preterm labor [...]

New Clinical Trial Read more

IBD CANCER AND SERIOUS INFECTIONS IN EUROPE

Mar 03, 2015 No Comments by

The primary objective of I-CARE is to assess prospectively the presence and the extent of safety concerns (cancers, especially, lymphoma, and serious infections risks) for anti-TNF alone or in combination with thiopurines among IBD patients. We will stratify the risk of cancers and serious infections according to IBD phenotype and disease activity (clinical, radiologic and [...]

New Clinical Trial Read more

A Pilot Evaluation of an Experimental BLI4600 Formulation for Bowel Preparation in Adult Patients Undergoing Colonoscopy

Mar 03, 2015 No Comments

To evaluate the safety, tolerance and efficacy of BLI4600 in multiple dosing regimens as a bowel preparation prior to colonoscopy in adult patients. Clinical Trial Conditions: Bowel Preparation for Colonoscopy Treatments in this Clinical Trial : BLI4600 bowel preparation, PEG based bowel preparation Clinical Trial Phase: Phase 2 Eligible Clinical Trial Participant Age : Between [...]

Read more

Pharmacokinetics and Pharmacodynamics of Mepolizumab Administered Subcutaneously in Children

Mar 03, 2015 No Comments

Mepolizumab is a humanized immunoglobulin G (IgG1) monoclonal antibody (mAb) that exhibits dose proportional and time-independent pharmacokinetics. This pharmacokinetic (PK) and pharmacodynamic (PD) study is conducted to support the use of mepolizumab in children aged 6 to 11 years with severe eosinophilic asthma and characterize the PK/PD of mepolizumab 40 milligrams (mg) or 100 mg [...]

Read more

Effects of Tremella Fuciformis on Improvement in Cognitive-Bio-Markers of Cognitive Functions

Mar 03, 2015 No Comments

The objective of this study is to demonstrate the cognitive enhancement effect and safety of Tremella Fuciformis, using the cognitive and clinical indicators (e.g. memory, attention, and psychomotor speed) and the latest brain imaging methods for healthy adults suffering subjective cognitive impairment. Clinical Trial Conditions: Healthy Adults With Subjective Memory Complaints Treatments in this Clinical [...]

Read more

The Role of Bifidobacterium Animalis Ssp Lactis DR10 Supplementation in Women During Pregnancy and Lactation on Breast Milk IL-8 and Gut Mucosa Integrity in Infant

Mar 03, 2015 No Comments

Hopefully this research can help to provide the optimal nutrition management from pregnancy so that the babies wiil born with better quality of health and reduce the morbidity and mortality. Until now, there is no data regarding probiotics in Indonesien breastmilk and the role of probiotics supplementation on pregnant women to the baby especially from [...]

Read more

Study to Investigate the Pharmacokinetics (PK) Safety and Tolerability of Retosiban in Healthy Japanese Women

Mar 03, 2015 No Comments

This study in healthy, adult Japanese women will characterize the PK, safety and tolerability of retosiban at the therapeutic doses planned to be evaluated in Phase 3. The PK data will be compared to a sub-set of Caucasian women given the same dose of retosiban. This study has two cohorts, cohort 1 will be a [...]

Read more

Pharmacokinetics of Zanamivir After Single and Repeated Dose Infusion Administration in Healthy Chinese Adults

Mar 03, 2015 No Comments

Zanamivir is a potent and highly selective inhibitor of the influenza virus neuraminidase. Intravenous (IV) zanamivir is being developed for treatment of hospitalized patients with influenza, especially for those patients who may be in greatest need of parenteral influenza antiviral agents. This study is a pharmacokinetic (PK) study to evaluate the safety/tolerability and pharmacokinetic profiles [...]

Read more

Accuracy of Electrohysterography in Assessing Intrauterine Pressure

Feb 27, 2015 No Comments

This is a case control prospective study aiming to investigate the accuracy of the electrohysterography (EHG) compared to the intrauterine pressure catheter ( IUPC) that is commonly used in delivery room. Women in second phase of labor – indicated for insertion of IUPC will be asked to participate . Patients that will give their informed [...]

Read more

The Analgesic Effect of Combined Nerve Block and Systemic High Dose Glucocorticoid After Total Knee Arthroplasty.

Feb 27, 2015 No Comments

Purpose: The purpose of this study is to evaluate the postoperative analgesic effect of a combined Saphenous nerve block and Obturator nerve block with local infiltration analgesia in the tissue around the knee after total kneearthroplasty. In the combined nerve blocks we use a mixture of Ropivacaine and Adrenaline combined with high dose systemic dexamethasone [...]

Read more

Food Effect Study of Febuxostat XR in Healthy Participants

Feb 27, 2015 No Comments

The purpose of this study is to assess the effect of food on the bio availability of Febuxostat after a single oral dose of 80 mg febuxostat XR and to evaluate the PK of Febuxostat after single oral doses of 40 and 80 mg Febuxostat XR. Clinical Trial Conditions: Gout Treatments in this Clinical Trial [...]

Read more

Sequence Variations of Genes in the Estrogen Pathway and Perinatal Depression

Feb 27, 2015 No Comments

To elucidate the disease pathway of perinatal depression by identifying genetic variants which could play a role in predisposing to the condition and/or lead to better understanding of the pathogenesis of the condition. This is achieved by investigating for associations between oestrogen receptor genetic variants and perinatal depression. Clinical Trial Conditions: Postnatal Depression, Genetic Predisposition [...]

Read more

Characterization of Methylation Patterns in Lung Cancer

Feb 27, 2015 No Comments

In this study the investigators will collect Blood,sputum and saliva samples for Characterization of Methylation Patterns in lung Cancer. Clinical Trial Conditions: Lung Cancer Eligible Clinical Trial Participant Age : Between 18 years to 65 years Can Healthy Volunteers Participate: No Clinical Trial Lead Sponsor: Nucleix Ltd. Detailed Clinical Trial Description: In this study the [...]

Read more

Chronic Pain Dynamic Psychophysical Tests and Genetic Screening

Feb 27, 2015 No Comments

Incidence and risk factors for persistent post surgical pain after Caesarean section are investigated. Demographic, psychophysical testing and genetic screening factors are performed in the perioperative period. Phone survey is performed to investigate the incidence of persistent post surgical pain after Caesarean section. Clinical Trial Conditions: Pain Eligible Clinical Trial Participant Age : Between 21 [...]

Read more

A Phase II Trial of LDK378 in ROS1 and /or ALK Over-expressed Advanced Intrahepatic or Hilar Cholangiocarcinoma

Feb 27, 2015 No Comments

Primary objective: To investigate the objective response rate in patients with ROS1 or ALK over-expressed locally advanced, or metastatic intrahepatic or hilar cholangiocarcinoma receiving LDK378 Secondary objectives:The progression-free survival ,The disease control rate ,The overall survival ,The toxicity profiles , The correlation between clinical outcomes and the potential predictive biomarker for tumor response Clinical Trial [...]

Read more

The Effects of Connective Tissue Manipulation and Abdominal Massage in Patients With Chronic Constipation

Feb 27, 2015 No Comments

The aim of this study is to investigate the effect of connective tissue manipulation and abdominal massage on severity of constipation and health related quality of life in patients with chronic constipation. According to literature, there are studies that investigate the effects of abdominal massage on bowel movements. But there is no randomized controlled trial, [...]

Read more

Pilot Study of Redirected Autologous T Cells Engineered to Contain Humanized Anti-CD19 in Patients With Relapsed or Refractory CD19+ Leukemia and Lymphoma Previously Treated With Cell Therapy

Feb 27, 2015 No Comments

This is a pilot study to evaluate humanized CD19 redirected autologous T cells (or huCART19 cells) in patients with relapsed or refractory CD19+ leukemia and lymphoma that was previously treated with cell therapy. This study is targeting pediatric patients aged 1-24 years with CD19+ B cell malignancies with no available curative treatment options (such as [...]

Read more

A Study to Evaluate the Efficacy of an Acellular Dermal Template for the Treatment of Full Thickness Skin Defects

Feb 27, 2015 No Comments

In this study the efficacy of an acellular dermal template (Novomaix), combined with split thickness skin grafts, for use in patients with full thickness skin defects, is tested. Results will be compared intra-patient with those obtained after conventional treatment with split thickness skin grafts. The investigators expect this treatment to provide better outcome regarding scar [...]

Read more

Website Application Based Education and Text Messaging in Improving Skin Wound Care in Patients Undergoing Mohs Surgery

Feb 27, 2015 No Comments

This randomized clinical trial studies how well website application (web app) based education and text messaging works in improving skin wound care in patients undergoing Mohs surgery (a surgical procedure used to treat skin cancer). Website application and text messaging based education may help patients stick to wound care instructions before and after surgery, lower [...]

Read more

Improving Balance and Mobility

Feb 27, 2015 No Comments

Falls are dangerous leading to injuries and even death. The VA has made fall prevention a priority but effective programs only reduce falls by 30%. Tai Chi, a standing exercise program, has been effective at improving balance but may not prevent falls. Most falls occur during walking when an individual experiences a slip or a [...]

Read more

Bipolar Ventricular Tachycardia (VT) Study

Feb 27, 2015 No Comments

This non-randomized study will examine the safety and efficacy of irrigated bipolar radiofrequency (RF) ablation in the treatment of ventricular tachycardia (VT) in patients for whom standard VT unipolar RF ablation has been unsuccessful. VT is a serious abnormality of the heart's electrical system. Ablation is a procedure that cauterizes heart tissue using catheters (long [...]

Read more

Helium-oxygen Gas Mixtures Delivered by a High Flow Nasal Cannula in Bronchiolitis

Feb 27, 2015 No Comments

The aim of this prospective pilot study is to determine the effect of heliox delivered via a proprietary calibrated heated and humidified high flow nasal cannula (HFNC) system (Vapotherm Precision Flow Heliox) in children ages 0-24 months with severe bronchiolitis. Clinical Trial Conditions: Bronchiolitis, Heliox, Pediatrics Treatments in this Clinical Trial : Vapotherm-Heliox Eligible Clinical [...]

Read more

IV Paracetamol Versus IV Dexketoprofen in Dysmenorrhea

Feb 27, 2015 No Comments

Patients presented with dysmenorrhea composed the study population. One gram paracetamol and 50 mg dexketoprofen in 100 ml saline with a rapid infusion were compared in ceasing dysmenorrhea in emergency department. Clinical Trial Conditions: Dysmenorrhea Treatments in this Clinical Trial : Paracetamol, Dexketoprofen Clinical Trial Phase: Phase 4 Eligible Clinical Trial Participant Age : Between [...]

Read more

Exparel as a Nerve Block for Severe Hand Pain

Feb 27, 2015 No Comments

The purpose of this study is to investigate whether the use of the study drug (Exparel) is safe and effective for treating circulation problems and pain in the hand or fingers. Clinical Trial Conditions: CREST Syndrome, Peripheral Vascular Disease, Raynaud Disease, Scleroderma, Diffuse Treatments in this Clinical Trial : liposomal bupivacaine Eligible Clinical Trial Participant [...]

Read more
By: ifood.tv