By: ifood.tv

Efficacy Study on Silver-coated ETT Cleaned With a Novel Device

Apr 22, 2014 No Comments by

The purpose of this study is to test the efficacy of a novel cleaning device in keeping silver-coated endotracheal tubes free from bacterial colonization. Clinical Trial Conditions: Ventilator Associated Pneumonia, Critically Ill Treatments in this Clinical Trial : ETT cleaning maneuver Eligible Clinical Trial Participant Age : Between 18 years to 100 years Can Healthy [...]

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Decreasing the Incidence of Delirium After Cardiac Surgery

Apr 22, 2014 No Comments by

In critically ill surgical patients, delirium (confusion and disorientation) is extremely common and is associated with longer hospital length of stay, mortality, cost, and long term cognitive impairment. The goal of the study is to establish whether benzodiazepines (a sedative, anti-anxiety drug) should be used as part of standard of care or be eliminated by [...]

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Inpatient Versus Outpatient Rehabilitation After TKA

Apr 22, 2014 No Comments by

The purpose of this study is to compare inpatient and outpatient rehabilitation following total knee arthroplasty. Outpatient rehabilitation should be provided at the same level of quality as inpatient care. Thus, it is assumed that outpatient rehabilitation is non-inferior to the inpatient standard-of-care therapy. Clinical Trial Conditions: Total Knee Arthroplasty Treatments in this Clinical Trial [...]

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Blood Volume and Hemodynamic Analysis in Patients With Chronic Heart Failure

Apr 22, 2014 No Comments

The primary hypothesis is that patients with HFREF (heart failure with reduced ejection fraction) will demonstrate a markedly expanded intravascular volume which will correlate with elevated right heart hemodynamics and increased venous capacitance parameters, whereas patients with HFPEF(heart failure with preserved ejection fraction) will demonstrate euvolemia to mild volume expansion and a lack of correlation [...]

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A Study to Compare a New Drug for Type 2 Diabetes to Placebo and to a Treatment Already Available for Type 2 Diabetes

Apr 22, 2014 No Comments

The main purpose of this study is to compare the safety and effectiveness of the study drug known as LY2944876 to exenatide extended-release and placebo in participants with type 2 diabetes mellitus. All drugs will be given by an injection under the skin. Participants remain on stable doses of metformin, as prescribed by their personal [...]

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Evaluating SINE KPT-330 in Treating Patients With Melanoma That Cannot Be Removed By Surgery

Apr 22, 2014 No Comments

This phase I clinical trial studies the side effects of selinexor in treating patients with melanoma that cannot be removed by surgery. Drugs used in chemotherapy, such as selinexor, may stop the growth of tumor cells, by stopping them from dividing. Clinical Trial Conditions: Recurrent Melanoma Treatments in this Clinical Trial : selinexor, Correlative studies [...]

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52-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D)

Apr 22, 2014 No Comments

Irritable Bowel Syndrome with diarrhoea (IBS-D) is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort and diarrhoea. This trial aims at the evaluation of the efficacy and safety of oral ibodutant 10 mg once daily as compared to placebo in women with IBS-D over a 12-week treatment period. Clinical Trial [...]

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Investigating Lysosomal Storage Diseases in Minority Groups

Apr 22, 2014 No Comments

Although lysosomal storage disorders, such as Fabry disease, Gaucher disease, and Pompe disease, represent serious challenges in the healthcare system, no study has yet investigated the prevalence of these diseases in the US. Frequently, patients show progressive worsening of symptoms for several years before they get diagnosed. Since many of these diseases can be managed [...]

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Carvedilol PAH A Pilot Study of Efficacy and Safety

Apr 22, 2014 No Comments

Estimate the effect of chronic beta-adrenergic receptor blockade with carvedilol on RV function in patients with PAH. Assess the safety and tolerability of chronic carvedilol therapy in patients with PAH Clinical Trial Conditions: Pulmonary Hypertension, Cardiac MRI <40 Treatments in this Clinical Trial : carvedilol Clinical Trial Phase: Phase 2 Eligible Clinical Trial Participant Age [...]

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Ruxolitinib in Combination With Pemetrexed/Cisplatin in Non Small Cell Lung Cancer

Apr 22, 2014 No Comments

The purpose of this study is to determine if ruxolitinib, in combination with Pemetrexed/Cisplatin and Pemetrexed Maintenance, is safe and effective in the treatment of nonsquamous non-small cell lung cancer (NSCLC) that is Stage IIIB, Stage IV, or recurrent. Clinical Trial Conditions: Carcinoma, Non-Small-Cell Lung Treatments in this Clinical Trial : Ruxolitinib, Placebo, Pemetrexed, Cisplatin [...]

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Topical PluroGel PN for the Treatment of Mildly Infected Diabetic Foot Ulcers

Apr 22, 2014 No Comments

This is an open label study of subjects who have failed Protocol PGN-1300. Adult subjects (greater than 18 years old) who present with a mildly infected diabetic foot ulcer (IDSA criteria) having full thickness (i.e., through the dermis but not involving joint capsule, tendon, and bone) and have failed PGN-1300. Subjects must also provide informed [...]

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Rapid Determination Of The Clinical Utility Of Perampanel For The Treatment Of Alcohol Dependence

Apr 22, 2014 No Comments

The purpose of this study is to determine whether perampanel alters the response to alcohol for heavy drinkers. It is hypothesized that perampanel will reduce the rewarding and reinforcing properties of alcohol in the laboratory setting. Clinical Trial Conditions: Alcoholism Treatments in this Clinical Trial : Perampanel, Placebo Eligible Clinical Trial Participant Age : Between [...]

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Study to Detect Biomarker Gradients in Coronary Arteries Using the Liquid Biopsy System

Apr 22, 2014 No Comments

The Liquid Biopsy System (LBS) is a new catheter (thin tube) designed for sampling blood directly from coronary arteries. These arteries supply blood to muscles of the heart and can become blocked by 'plaques' leading to chest pain (angina) and heart attacks. Recent research has shown that development of ' plaques' inside coronary arteries is [...]

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Comparative Effectiveness of Unilateral vs. Bilateral Pulmonary Collapse in Cardiac De-airing

Apr 22, 2014 No Comments

To compare the effectiveness of unilateral pulmonary collapse (right lung) to bilateral pulmonary collapse for cardiac de-airing in open left-sided heart surgery. Clinical Trial Conditions: Brain Ischemia, Reduction of Cerebral Air Emboli Treatments in this Clinical Trial : Bilateral Open Pleurae, Right Pleura Open Eligible Clinical Trial Participant Age : Between 18 years to 100 [...]

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Study of Ruxolitinib in Colorectal Cancer Patients

Apr 22, 2014 No Comments

The purpose of this study is to determine if ruxolitinib, in combination with regorafenib, is safe and effective in the treatment of metastatic colorectal cancer. Clinical Trial Conditions: Metastatic Colorectal Cancer Treatments in this Clinical Trial : Ruxolitinib, Regorafenib, Placebo Clinical Trial Phase: Phase 2 Eligible Clinical Trial Participant Age : Between 18 years to [...]

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Fetal Viability Estimation in Egypt

Apr 22, 2014 No Comments

Due to the discrepancy between the Egyptian and the conventional definition of miscarriage or live birth, there seemed to be a need for a study that ends up with reaching a definition for the mentioned terms. live birth is known to be for fetus born after 20 weeks or of weight more than 500 grams, [...]

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Investigating the Effects of a Psycho-educational Support Group Therapy on Cancer Caregivers’ Burden and Quality of Life

Apr 22, 2014 No Comments

This is a study to determine the effectiveness of a Group Therapy that provides psycho-education and support for caregivers of cancer patients. Caregivers must be between 21 and 64 years of age and be willing to attend a one-hour a week program for four weeks. The sessions will be in English, and a set of [...]

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Hemodynamic Effects of Terlipressin and High Dose Octreotide

Apr 22, 2014 No Comments

The purpose of the study is to find patients's response to terlipressin and octreotide during hepatic venous pressure gradient measurement by observing portal and systemic hemodynamics. Clinical Trial Conditions: Gastric and Esophageal Varices Treatments in this Clinical Trial : Terlipressin, Octreotide Clinical Trial Phase: Phase 4 Eligible Clinical Trial Participant Age : Between 18 years [...]

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TIPS Combined With Variceal Embolization for the Prevention of Variceal Rebleeding in Patients With Cirrhosis

Apr 22, 2014 No Comments

The purpose of this study is to determine whether TIPS combined with variceal embolization are effective in the prevention of variceal rebleeding in patients with liver cirrhosis. Clinical Trial Conditions: Liver Cirrhosis Treatments in this Clinical Trial : TIPS, Embolization Eligible Clinical Trial Participant Age : Between 18 years to 75 years Can Healthy Volunteers [...]

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A Study of Ruxolitinib in Combination With Capecitabine in Subjects With Advanced or Metastatic HER2-negative Breast Cancer

Apr 22, 2014 No Comments

This is a randomized, double-blind, placebo controlled clinical trial comparing the overall survival of women with advanced or metastatic HER2-negative breast cancer who receive treatment with capecitabine in combination with ruxolitinib versus those who receive treatment with capecitabine alone. Clinical Trial Conditions: Advanced or Metastatic HER2-negative Breast Cancer Treatments in this Clinical Trial : Ruxolitinib, [...]

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Eribulin Mesylate and Everolimus in Treating Patients With Triple-Negative Metastatic Breast Cancer

Apr 22, 2014 No Comments

This phase I trial studies the side effects and best dose of eribulin mesylate and everolimus in treating patients with triple-negative metastatic breast cancer. Eribulin mesylate and everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving eribulin mesylate together with everolimus may be a safe [...]

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Phase 1 Study of Multiple-Dose Pharmacokinetics of Cenicriviroc in Subjects With Mild and Moderate Hepatic Impairment

Apr 22, 2014 No Comments

To determine whether CVC exposures are altered in subjects with impaired hepatic function, compared to subjects with normal hepatic function. The results will help guide the clinical use of CVC in patients with hepatic impairment, determine the extent of PK changes, if any, and identify the potential need for dose adjustments of CVC in this [...]

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Functional Neuroimage in Assessment of Post-stroke Aphasia

Apr 22, 2014 No Comments

The substantial efficacy and the possible mechanism of repetitive transcranial magnetic stimulation (rTMS) improving language recovery remained unclear. It is hypothesized that the rTMS was associated with increased synaptic connection and neural regeneration which can be evaluated via functional neuroimage and neurofiber imaging analysis. The effect of rTMS intervention was monitored by clinical testing and [...]

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Application of Digital Techniques in Intraoral Condylectomy Via Coronoid Process Resection

Apr 22, 2014 No Comments

This study will apply the digital techniques to do the condylectomy through an intraoral approach without needing to do the intraoral vertical ramus osteotomy (IVRO). This new surgical technique will greatly maintain the TMJ anatomy structure, reduce the risk and increase the precision of the operation procedure. Clinical Trial Conditions: Condylectomy Through an Intraoral Approach [...]

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Reconstruction of Interdental Papilla Using Hyaluronic Acid

Apr 22, 2014 No Comments

Objective and background: The aim of this study is to evaluate the clinical outcome of using the hyaluronic acid gel in reconstructing inter-dental papillae at the aesthetic zones in a follow-up period of six months. Materials and Methods: 30 interdental papilla deficiencies which would meet the the inclusion criteria will be evaluated. After applying local [...]

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By: ifood.tv