By: ifood.tv

Randomized Controlled Feasibility Trial of the Fearon Algorithm to Improve Management of Unstable Warfarin

Oct 17, 2014 No Comments by

Patients on warfarin but with unstable international normalized ratio (INR) will be recruited to a randomized trial comparing dosing based on an algorithm (Fearon algorithm, named after the mathematician Michael Fearon), which uses historical data to estimate patients' sensitivity to warfarin and to dose changes as well as the lag time until a dose adjustment [...]

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Changes in Renal Artery Movement Due to Respiration Before and After Fenestrated Endovascular Repair

Oct 17, 2014 No Comments by

Purpose: The purpose of this study is to evaluate the location within the renal artery of maximal angular displacement before and after fenestrated endovascular aortic repair (FEVAR) using CT with end-inspiration and end-expiration CT images before and after repair. Then, the renal artery segment with maximal angular displacement on each will be located and any [...]

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Effects of Home Based Exercise Therapy in Early Cirrhosis

Oct 17, 2014 No Comments by

Individuals with Cirrhosis have been shown to have a low aerobic capacity. While supervised exercise training has been shown to be an effective intervention to remedy this, there is currently no data on home based exercise interventions in this population. This study will evaluate the effects of a home based exercise program on the aerobic [...]

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Efficacy and Safety of Two Anti-T-lymphocyte Immune Globulin (ATG-F) Induction Regimens in Anew Kidney Transplant Patients

Oct 17, 2014 No Comments

To investigate the efficacy and safety of ATG-F induction regimen using a single dose of ATG-F compared with a five-day dose regimen of ATG-F in anew kidney transplant recipients. Clinical Trial Conditions: De Novo Kidney Transplant Patients Treatments in this Clinical Trial : ATG-F Clinical Trial Phase: Phase 4 Eligible Clinical Trial Participant Age : [...]

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Study of Freeze-dried Black Raspberry in Maintenance of Ulcerative Colitis

Oct 17, 2014 No Comments

This research study is about adding Black Raspberry powder to the treatment regimen of patients with ulcerative colitis who are currently in remission and doing well. Clinical Trial Conditions: Ulcerative Colitis Treatments in this Clinical Trial : Freeze-dried black raspberry powder Clinical Trial Phase: Phase 1 Eligible Clinical Trial Participant Age : Between 18 years [...]

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Occlusal-proximal ART Restorations in Primary Molars Using 2 Different Kinds of GIC

Oct 17, 2014 No Comments

The aim of this research is to investigate the survival rate and cost effectiveness of two brands of GIC as occlusal-proximal ART restorations. Also the survival rate of the tooth will be investigated. Clinical Trial Conditions: Dental Caries Treatments in this Clinical Trial : Occlusal-proximal ART restorations – Ketac Molar, Occlusal-proximal ART restorations – Vitro [...]

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Subsymptom Threshold Exercise Protocol Following Mild TBI

Oct 17, 2014 No Comments

The study will monitor outcomes of two interventions to develop a best practice in the treatment of mild Traumatic Brain Injury (mTBI). Clinical Trial Conditions: Traumatic Brain Injury Treatments in this Clinical Trial : STEP, Control Eligible Clinical Trial Participant Age : Between 14 years to 18 years Can Healthy Volunteers Participate: No Clinical Trial [...]

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Exploratory Study for the Validity of QuQu Scale

Oct 17, 2014 No Comments

Examine the construct validity, the group discriminant ability, and the inter-rater reliability of a novel dementia rating scale (QuQu scale: QUick QUestion scale) candidate for the evaluation of patients with Alzheimer Dementia (AD) Clinical Trial Conditions: Alzheimer Dementia Treatments in this Clinical Trial : Standard therapy of Alzheimer Dementia (AD), Observation Eligible Clinical Trial Participant [...]

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Ruxolitinib and Pracinostat Combination Therapy for Patients With Myelofibrosis (MF)

Oct 17, 2014 No Comments

The goal of this clinical research study is to learn if pracinostat, when given in combination with ruxolitinib, can help to control MF. The safety of this drug combination will also be studied. Clinical Trial Conditions: Myeloproliferative Diseases Treatments in this Clinical Trial : Ruxolitinib, Pracinostat, Questionnaire Clinical Trial Phase: Phase 2 Eligible Clinical Trial [...]

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Parental One-carbon Folate and Choline Nutrition Modulates Risk of Off-spring Cancer Development: Human Cohort Study

Oct 17, 2014 No Comments

Parental one-carbon nutrient intake (folic acid and choline) and the genetic polymorphisms of one-carbon metabolic enzyme were interact with regulating embryonic one-carbon metabolic environment, affect fetal DNA and RNA biosynthesis and methyl modification of the genome molecule, to promote the individual nutrient growth factor of growth and development. Inadequate maternal one-carbon nutrient intake combined with [...]

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Study of High-dose Influenza Vaccine Efficacy by Repeated Dosing In Gammopathy Patients

Oct 17, 2014 No Comments

A Pilot Study utilizing high dose trivalent influenza vaccine dose in a booster dosing schedule for patients with monoclonal gammopathies stratified by disease status Clinical Trial Conditions: Influenza, Gammopathy Treatments in this Clinical Trial : Fluzone Clinical Trial Phase: Phase 1 Eligible Clinical Trial Participant Age : Between 18 years to 100 years Can Healthy [...]

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A Patient-Centered Strategy for Improving Diabetes Prevention in Urban American Indians

Oct 17, 2014 No Comments

The goal of the proposed research is to identify effective patient-centered strategies to prevent diabetes in high-risk populations in real world settings. The investigators will accomplish this by conducting a randomized controlled trial comparing an enhanced Diabetes Prevention Program addressing psychosocial stressors to a standard version in a high-risk population of urban American Indian and [...]

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A Multicenter Double-Blind Randomized Placebo-Controlled Parallel-Group Phase 2 Study to Assess the Efficacy Safety and Tolerability of Velusetrag for the Treatment of Diabetic or Idiopathic Gastroparesis

Oct 17, 2014 No Comments

Study 0099 will explore the efficacy and safety of multiple doses of velusetrag in the treatment of symptoms in subjects with diabetic or idiopathic gastroparesis. Three dose levels of velusetrag will be evaluated and compared to placebo for approximately 12 weeks of therapy. In addition, the study will be used to evaluate the psychometric properties [...]

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A Prospective Comparison of Fluoroscopic Sonographic or Combined Approach for Renal Access in Percutaneous Nephrolithotomy

Oct 17, 2014 No Comments

Purpose: The aim of this present study is to compare the result of fluoroscopy, ultrasonograpghy (US) and US combined with fluoroscopy in the guidance of minimally invasive percutaneous nephrolithotomy (MPCNL). Methods: The investigators will enroll 450 patients who are candidates for MPCNL in our study. By simple random sampling technique, patients will be assigned to [...]

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Exercise Targeting Cognitive Impairment in Parkinson’s Disease

Oct 17, 2014 No Comments

The aim of this application is to compare and elucidate the effects of skill-based versus aerobic exercise versus control on mild cognitive impairment (MCI) of the executive function (EF) subtype in Parkinson's disease (PD); we hypothesize that skill-based exercise will result in the greatest improvement in EF and lead to modification of underlying neural substrates. [...]

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Effectiveness of Prolonged Use of IUD/Implant for Contraception

Oct 17, 2014 No Comments

This study will evaluate LNG-IUD and ENG implant users who are willing to use their contraception beyond the end of the FDA-approved duration. Implant users will also be offered to participate in an arm of the study that will randomize them to either keeping their implant in or have it removed and replaced with a [...]

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Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Male and Female

Oct 17, 2014 No Comments

The purpose of this trial is to investigate bioequivalence of a newly developed fixed dose combination (FDC) tablet containing empagliflozin and metformin extended release compared to the free combination of empagliflozin and metformin extended release under fed conditions. Clinical Trial Conditions: Healthy Treatments in this Clinical Trial : metformin, empagliflozin/metformin, empagliflozin Clinical Trial Phase: Phase [...]

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IV Acetaminophen vs IV Morphine for Pain Control in Pregnant Women

Oct 17, 2014 No Comments

Purpose: To determine if IV acetaminophen can 1) decrease pain in pregnancy women, 2)reduce the amount of opioid use in pregnant women who encounter pain, 3) reduce maternal and fetal adverse effects compared to opioids. Design: This is a comparative effective trial that is a randomized, controlled trial of IV acetaminophen vs. IV morphine in [...]

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A Phase 1 Study of PT-112 Injection in Subjects With Advanced Solid Tumors

Oct 17, 2014 No Comments

This is a Phase I, open-label, multi-center, non-randomized, dose-escalation study to be conducted in two parts: the Dose Escalation Phase and the Dose Confirmation Phase. The Dose Escalation Phase will determine the Maximum Tolerated Dose (MTD) and recommended Phase 2 dose(s) (RP2D) of PT-112 Injection and evaluate its safety and tolerability, PK (pharmacokinetic) and preliminary [...]

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Placebo- Controlled Study to Evaluate the Safety and Immunogenicity of the RSV-F Vaccine in Elderly Adults

Oct 17, 2014 No Comments

The purpose of this study is to evaluate the safety and immunogenicity of the RSV- F Vaccine in elderly subjects, as well as rate the incidence of medically- attended RSV disease in vaccine and placebo recipients. Clinical Trial Conditions: Respiratory Syncytial Virus (RSV) Treatments in this Clinical Trial : RSV-F Vaccine, Saline Placebo Clinical Trial [...]

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Randomized Controlled Trial of GLYX-13 in Individuals With Obsessive-Compulsive Disorder

Oct 17, 2014 No Comments

This research study tests whether GLYX-13 – an experimental drug that acts on a brain receptor called NMDA – can decrease symptoms of OCD within hours. This is not a treatment study. Results from this study will allow doctors and researchers to better understand if you and others with OCD may respond to a class [...]

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Hepatitis B Patients Under Oral Nucleos(t)Ide Treatment With Intermittent Assessment of Kidney Function

Oct 17, 2014 No Comments

Patients with chronic Hepatitis B who are under oral antiviral treatment for at least 6 months at study start will be monitored once yearly for kidney function changes within their routine outpatient visit. Therefore urine samples will be collected and some additional blood test will be done within the routine blood sampling. Clinical Trial Conditions: [...]

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Study to Evaluate Performance Usability Safety of Microwave Technology When Collecting Data From Patients With Stroke

Oct 17, 2014 No Comments

This is a prospective, open, multicenter study that will enroll patients admitted to and hospitalized at the Stroke Unit due to diagnosed stroke and healthy volunteers. The main purpose of the study is to evaluate the ability of the Microwave Technology to deliver adequate measurement data. Clinical Trial Conditions: Stroke, Healthy Treatments in this Clinical [...]

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McGrath Videolaryngoscopy for Nasotracheal Intubation

Oct 17, 2014 No Comments

McGrath videolaryngoscopy avoids the use of Magill forceps for nasotracheal intubation, thereby reducing intubation time and complications, especially in patients with a difficult airway. This study was performed to investigate whether McGrath videolaryngoscopy is superior to Macintosh laryngoscopy for routine nasotracheal intubation in expected normal airways, as judged by the time to intubation and ease [...]

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Amyloid and Tauopathy PET Imaging in Acute and Chronic Traumatic Brain Injury

Oct 17, 2014 No Comments

The potential long-term effects of Traumatic Brain Injury (TBI) are poorly understood. Repeated concussions have been associated with an elevated incidence of Alzheimer's disease (AD) along with a reduced age of onset. As repetitive TBI has been studied, a syndrome has now been identified: chronic traumatic encephalopathy (CTE). There are growing concerns about the long-term [...]

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By: ifood.tv